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Insulin Antagonists

Insulin antagonists are used to treat hypoglycemia in individuals with diabetes type 1 and type 2. They work by increasing glucose to raise blood sugar levels.

Why are insulin antagonists prescribed?

  1. Hypoglycemia (69%)
  2. Diabetes Type 1 (16%)
  3. Diabetes Type 2 (16%)
  4. Polyphagia (0%)

Key takeaways

Insulin antagonists are used to treat severe hypoglycemia (low blood sugar). Certain medications in this class can also be used before diagnostic imaging procedures, such as an MRI. When used to treat hypoglycemia, they increase blood glucose (sugar) levels, either by stimulating the liver to release stored glucose or by blocking the pancreas from releasing insulin. Insulin antagonists come in different forms, including injectable and nasal options. Examples include glucagon (Glucagen, Baqsimi, Gvoke), dasiglucagon (Zegalogue), and diazoxide (Proglycem). You can discuss with your healthcare team which option might be right for you.

Prices for popular Insulin Antagonists medications
Viewing 8 of 8 medications
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glucagon

as low as$47
GLUCAGON treats very low blood sugar (severe hypoglycemia) in an emergency. Call emergency services after using this medication. You may need additional treatment. Glucagon works by helping your liver release stored sugar into your blood, which raises your blood sugar (glucose) levels.
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Baqsimi

as low as$291
Baqsimi (glucagon) occurs naturally in the body. It increases blood sugar. This medicine is used as an emergency treatment for severe low blood sugar in diabetic patients, especially if they are not able to take sugar by mouth. Baqsimi is slightly less popular than other insulin antagonists. There are currently no generic alternatives to Baqsimi.

GoodRx has partnered with Inside RX and Eli Lilly to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Baqsimi is covered by most Medicare and insurance plans.
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Gvoke

as low as$318
GLUCAGON treats very low blood sugar (severe hypoglycemia) in an emergency. Call emergency services after using this medication. You may need additional treatment. Glucagon works by helping your liver release stored sugar into your blood, which raises your blood sugar (glucose) levels.
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Glucagen

as low as$171
GLUCAGON treats very low blood sugar (severe hypoglycemia) in an emergency. Call emergency services after using this medication. You may need additional treatment. Glucagon works by helping your liver release stored sugar into your blood, which raises your blood sugar (glucose) levels.
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Zegalogue

as low as$321
DASIGLUCAGON treats very low blood sugar (severe hypoglycemia) in an emergency. Call emergency services after using this medication. You may need additional treatment. Dasiglucagon works by helping your liver release stored sugar into your blood, which raises your blood sugar (glucose) levels.
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Proglycem

as low as$472
DIAZOXIDE treats low blood sugar (hypoglycemia) in people with conditions that cause their body to make too much insulin. It works by decreasing insulin levels in your body, which raises your blood sugar.
Gvoke Vialdx is part of the Insulin Antagonists class and treats Hypoglycemia, Diabetes Type 1 and Diabetes Type 2. Insulin antagonists are used to treat hypoglycemia in individuals with diabetes type 1 and type 2. They work by increasing glucose to raise blood sugar levels. Gvoke Vialdx is only available as a brand name drug.
Vykat XR is part of the Insulin Antagonists class and treats Polyphagia. Insulin antagonists are used to treat hypoglycemia in individuals with diabetes type 1 and type 2. They work by increasing glucose to raise blood sugar levels. Vykat XR is only available as a brand name drug.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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