Chlo Hist
Chlo Hist is a combination medication containing chlophedianol (a cough suppressant) and dexbrompheniramine (an antihistamine). It can be taken by adults and children to help with certain allergy and common cold symptoms, such as cough, runny nose, and itchy eyes. Chlo Hist (chlophedianol / dexbrompheniramine) is taken by mouth, typically every 6 hours, as needed. It's available as a brand name oral solution (liquid) that you can buy over the counter. Some side effects of this medication include include dizziness and sleepiness.
What is Chlo Hist (chlophedianol / dexbrompheniramine) ?
What is Chlo Hist (chlophedianol / dexbrompheniramine) used for?
Temporary relief of:
- Cough from minor throat irritation
- Runny nose
- Sneezing
- Itchy nose or throat
- Itchy and watery eyes
How Chlo Hist (chlophedianol / dexbrompheniramine) works
Chlo Hist (chlophedianol / dexbrompheniramine) is a combination of two medications.
- Chlophedianol is a cough suppressant. It works by blocking signals from the part of your brain that makes you cough.
- Dexbrompheniramine is a first-generation antihistamine. It blocks a natural substance in your body called histamine. This helps relieve runny nose, itchy nose, and sneezing.
Drug facts
| Common Brands | Chlo Hist |
|---|---|
| Drug Class | Cough suppressant / Antihistamine |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Over-the-counter |
Side effects of Chlo Hist (chlophedianol / dexbrompheniramine)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Sleepiness
- Dizziness
- Constipation
- Blurry vision
- Dry mouth
Less Common Side Effects
- Stomach upset
- Trouble urinating
Chlo Hist (chlophedianol / dexbrompheniramine) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Excessive sleepiness or dizziness
The following Chlo Hist (chlophedianol / dexbrompheniramine) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
- Trouble passing urine
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Confusion
- Constipation
- Dizziness
- Drowsiness
- Dry mouth
- Fatigue
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Pros and cons of Chlo Hist (chlophedianol / dexbrompheniramine)
Pros
- Available over the counter
- Liquid, so good option if you have trouble swallowing pills
- Easier to take a combination product instead of 2 separate medications to treat cough or allergy symptoms
- Option for children ages 6 years and older
Cons
- Can cause sleepiness or dizziness
- Can cause excitability (hyperactivity) in children
- Might need to take multiple times a day
- Older adults at higher risk for drowsiness
Pharmacist tips for Chlo Hist (chlophedianol / dexbrompheniramine)
- You might feel sleepy after taking Chlo Hist (chlophedianol / dexbrompheniramine) . Don't drive or do anything that requires you to be alert until you know how Chlo Hist (chlophedianol / dexbrompheniramine) affects you.
- It's best to avoid drinking alcohol while taking Chlo Hist (chlophedianol / dexbrompheniramine) because doing so can worsen sleepiness and dizziness. And if you have a cold or flu, drinking alcohol can make it harder for your body to recover.
- While Chlo Hist (chlophedianol / dexbrompheniramine) usually makes adults sleepy, it's possible for children who use Chlo Hist (chlophedianol / dexbrompheniramine) to become overly excited or energetic. If this happens to your child, speak to your child's pediatrician.
- Be sure to use a medication dose cup, spoon, or syringe to measure out your dose of Chlo Hist (chlophedianol / dexbrompheniramine) . Don't use household spoons because they're not accurate and might cause you to take the wrong amount of this medication.
- Don't start any new medications while taking Chlo Hist (chlophedianol / dexbrompheniramine) , especially other cough suppressants (antitussives) or antihistamines, without talking to your primary care provider or pharmacist first. Doing so can raise your risk of overdose and severe side effects, including seizures, hallucinations (seeing things that are not real), daytime sleepiness, dizziness, or even death.
- Stop taking Chlo Hist (chlophedianol / dexbrompheniramine) and talk to your primary care provider if your cough lasts for longer than 1 week, goes away and comes back, or you also have a fever, rash, or headache. A cough that doesn't go away can be a sign of a serious condition that you should get checked out.
Risks and warnings for Chlo Hist (chlophedianol / dexbrompheniramine)
Chlo Hist (chlophedianol / dexbrompheniramine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Excessive sleepiness
- Risk factors: Taking more than the recommended dose | Taking other medications that cause drowsiness | Drinking alcohol
Chlo Hist (chlophedianol / dexbrompheniramine) can make you very sleepy, which can affect your ability to focus, think, or react. This side effect is more likely to happen or be more intense if you're over 65 years old, drink alcohol while you're taking this medication, or take other medications that cause sleepiness (e.g., opioids, benzodiazepines, sleep medications). Don't drive or operate machinery until you know how Chlo Hist (chlophedianol / dexbrompheniramine) affects you.
Accidental overdose
Chlo Hist (chlophedianol / dexbrompheniramine) contains a cough suppressant (chlophedianol) and an antihistamine (dexbrompheniramine), which are in many other over-the-counter products. Using more than one medication containing a cough suppressant and antihistamine, including products used on the skin, can lead to an accidental overdose. This can result in serious side effects, including daytime sleepiness, dizziness, seizures, hallucinations (seeing things that aren't real), or even death.
Tell your primary care provider or pharmacist about the medications you take before starting Chlo Hist (chlophedianol / dexbrompheniramine) to make sure it's safe for you. Don't start any new medications while taking Chlo Hist (chlophedianol / dexbrompheniramine) without talking to your care team. To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has a cough suppressant or an antihistamine, ask your pharmacist. If you or your loved one experiences an accidental overdose, get medical help right away or contact a poison control center at 1-800-222-1222.
Worsening of medical conditions
- Risk factors: Cough from smoking, asthma, or emphysema | Mucus-producing cough | Breathing problems (e.g., emphysema, long-term bronchitis) | Glaucoma | Urinary problems
Don't take Chlo Hist (chlophedianol / dexbrompheniramine) if you have any of the risk factors listed above unless your primary care provider said it's safe to do so. Taking Chlo Hist (chlophedianol / dexbrompheniramine) can worsen your condition(s) and cause serious side effects. Make sure your primary care provider knows about all medical conditions you have or have had in the past before starting Chlo Hist (chlophedianol / dexbrompheniramine) .
Chlo Hist (chlophedianol / dexbrompheniramine) dosage
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 473ml of 12.5mg/1mg/5ml | 1 bottle | $49.95 | $49.95 |
| 120ml of 12.5mg/1mg/5ml | 1 bottle | $16.75 | $16.75 |
Typical dosage for Chlo Hist (chlophedianol / dexbrompheniramine)
Each 5 mL of Chlo Hist (chlophedianol / dexbrompheniramine) contains 12.5 mg of chlophedianol and 1 mg of dexbrompheniramine.
- Adults and children ages 12 years and older: The typical dose is 10 mL by mouth every 6 hours. Don't take more than 40 mL in 24 hours.
- Children ages 6 to under 12 years old: The typical dose is 5 mL by mouth every 6 hours. Don't take more than 20 mL in 24 hours.
- Child under 6 years old: Don't use. Talk with your child's pediatrician.