The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Lower blood cell counts (up to 99%)
- Fever (96%)
- Cytokine release syndrome (95%)
- Low immunoglobulins levels (94%)
- Low blood pressure (51%)
- Muscle pain (48%)
- Tiredness (47%)
- Infections (41%)
- Diarrhea (33%)
- Chills (33%)
- Nausea (31%)
Less Common Side Effects
- Lower appetite
- Headache
- Fast heartbeat
- Dizziness
- Swelling
- Blood clotting problems
Carvykti serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Cytokine release syndrome: Fever, trouble breathing, dizziness, chills, low blood pressure, fast heartbeat, headache, tiredness
- Serious nervous system problems: headache, confusion, changes in personality, depression, difficulty speaking, difficulty writing, weakness in the arms and legs, tingling in the hands and feet, tremor, slower movement, seizures
- Serious infections: fever, body aches, fast heartbeat, chills
- Bleeding (from low platelets): nosebleeds, blood in urine, blood in stool, unexplained bruising
Source: DailyMed
The following Carvykti side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
- Fever, rash, swollen lymph nodes, confusion, trouble walking, loss of balance or coordination, seizures
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Muscle stiffness or spasms, tremors or shaking, loss of balance or coordination, shuffling walk
- Numbness or weakness of the face, uneven smile
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Severe back pain, numbness or weakness of the hands, arms, legs, or feet, loss of coordination, loss of bowel or bladder control
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Diarrhea
- Fatigue
- Headache
- Loss of appetite
- Muscle pain
- Nausea

