The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low white blood cell levels (98%)
- Fever (55%)
- Cytokine release syndrome (49%)
- Low platelet levels ( 48%)
- Muscle pain (36%)
- Headache ( 34%)
- Low red blood cell levels (32%)
- Tiredness (28%)
- Nausea (24%)
- Constipation (20%)
- Dizziness (20%)
Note: Side effects listed were reported by people who received Breyanzi for large B-cell lymphoma.
Less Common Side Effects
- Trouble sleeping
- Tremors
- Muscle spasms or weakness
- Diarrhea
- Stomach pain
- Vomiting
- Swelling from fluids
- Infections
- Rash
- Bleeding
Breyanzi serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Cytokine release syndrome: Fever, trouble breathing, chills, low blood pressure, changes in heart rhythm, headache
- Serious nervous system problems: headache, confusion, difficulty speaking, difficulty writing, seizures
- Serious infection: fever, body aches, fast heartbeat, chills
- Serious bleeding (from low platelets): nosebleeds, blood in urine, blood in stool, bruising that won't go away, bleeding that's difficult to stop, stomach pains
Source: DailyMed
The following Breyanzi side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
- Fever, rash, swollen lymph nodes, confusion, trouble walking, loss of balance or coordination, seizures
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Constipation
- Diarrhea
- Dizziness
- Fatigue
- Headache
- Muscle pain
- Nausea
