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Avandaryl
Avandaryl (rosiglitazone / glimepiride) is a combination medication used together with diet and exercise to control blood sugar in people with type 2 diabetes. It's no longer available in the United States, because it was discontinued.
Last reviewed on July 7, 2022
What is Avandaryl (rosiglitazone / glimepiride)?
What is Avandaryl (rosiglitazone / glimepiride) used for?
Type 2 diabetes
How Avandaryl (rosiglitazone / glimepiride) works
Are you looking for information on Avandia (rosiglitazone) or glimepiride (Amaryl) instead?
Drug Facts
Common BrandsAvandaryl (brand no longer available)
Drug ClassThiazolidinedione / Sulfonylurea
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Avandaryl (rosiglitazone / glimepiride)
What is Avandaryl (rosiglitazone / glimepiride)?
Avandaryl (rosiglitazone / glimepiride) is made up of two medications that help lower your blood sugar. Rosiglitazone is a glitazone (also known as thiazolidinedione) that helps your body use insulin to lower your blood sugar; insulin converts blood sugar into energy that your body can use. Glimepiride is a sulfonylurea that works by telling your pancreas to release insulin to lower your blood sugar.
Is Avandaryl (rosiglitazone / glimepiride) still available?
No, Avandaryl (rosiglitazone / glimepiride) has been discontinued and is no longer available in the United States. It's not clear why Avandaryl (rosiglitazone / glimepiride) was discontinued, but it wasn't due to any safety reasons or how well it worked.
What can I take in place of Avandaryl (rosiglitazone / glimepiride)?
While Avandaryl (rosiglitazone / glimepiride) has been discontinued, rosiglitazone and glimepiride are both still available today as single-ingredient medications. Additionally, there are several other medications for type 2 diabetes that are available and commonly used today. Your healthcare provider will help guide you to an alternative medication that's best for you.
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Interactions between Avandaryl (rosiglitazone / glimepiride) and other drugs
Avandaryl (rosiglitazone / glimepiride) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Avandaryl (rosiglitazone / glimepiride). Please note that only the generic name of each medication is listed below.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abiraterone Acetate
- Aspirin
- Balofloxacin
- Besifloxacin
- Ceritinib
- Chloroquine
- Ciprofloxacin
- Desmopressin
- Disopyramide
- Dulaglutide
- Enoxacin
- Entacapone
- Fleroxacin
- Flumequine
- Gatifloxacin
- Gemifloxacin
- Hydroxychloroquine
- Insulin
- Insulin Aspart, Recombinant
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glargine, Recombinant
- Insulin Glulisine
- Insulin Lispro, Recombinant
- Isoniazid
- Lanreotide
- Letermovir
- Levofloxacin
- Lixisenatide
- Lomefloxacin
- Metreleptin
- Miconazole
- Moxifloxacin
- Nadifloxacin
- Norfloxacin
- Octreotide
- Ofloxacin
- Pasireotide
- Pazufloxacin
- Pefloxacin
- Pioglitazone
- Pixantrone
- Porfimer
- Prulifloxacin
- Rufloxacin
- Sitagliptin
- Sparfloxacin
- Thioctic Acid
- Tosufloxacin
- Voriconazole
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acebutolol
- Aminolevulinic Acid
- Atenolol
- Betaxolol
- Bisoprolol
- Bitter Melon
- Carteolol
- Carvedilol
- Celiprolol
- Colesevelam
- Esmolol
- Fenofibrate
- Fenofibric Acid
- Fenugreek
- Furazolidone
- Gemfibrozil
- Glucomannan
- Guar Gum
- Iproniazid
- Isocarboxazid
- Labetalol
- Levobunolol
- Linezolid
- Methylene Blue
- Metipranolol
- Metoprolol
- Moclobemide
- Nadolol
- Nebivolol
- Nialamide
- Oxprenolol
- Penbutolol
- Phenelzine
- Pindolol
- Practolol
- Procarbazine
- Propranolol
- Psyllium
- Rasagiline
- Rifampin
- Safinamide
- Saxagliptin
- Selegiline
- Sotalol
- Timolol
- Tranylcypromine
- Trimethoprim
What are alternatives to Avandaryl (rosiglitazone / glimepiride)?
There are a number of medications that your doctor can prescribe in place of Avandaryl (rosiglitazone / glimepiride). Compare a few possible alternatives below.
Used for:
Type 2 diabetes in adults
Used for:
Type 2 diabetes in adults
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