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Atropine Coupon - Atropine 5ml of 1% eye dropper

atropine

Generic Isopto Atropine
Used for Heart Attack, Pupil Dilation
Used for Heart Attack, Pupil Dilation

Atropine (Isopto Atropine) is an eye medication that's used to dilate or widen the pupil (the black part of your eye). It's also used to treat lazy eye. This medication is an anticholinergic that works to make the pupil bigger. Atropine (Isopto Atropine) comes as eye drops and an eye ointment. The usual dosage is to apply the medication to the eye(s) 1 to 2 times daily. It can be used in people 3 months and up according to the eye specialist's instructions. Side effects include temporary eye pain, stinging, eye sensitivity to light, and blurry vision. Atropine (Isopto Atropine) is available as a brand-name and generic medication.

Last reviewed on August 27, 2021
basics-icon

What is Atropine (Isopto Atropine)?

What is Atropine (Isopto Atropine) used for?

  • Pupil dilation (e.g., for eye exams) - eye drops and eye ointment

  • Temporary paralysis of the eye muscle (cycloplegia) - eye drops and eye ointment

  • Treatment for lazy eye - eye drops only

How Atropine (Isopto Atropine) works

Atropine (Isopto Atropine) is an anticholinergic medication. When it's placed in the eye, the medication blocks signals that normally make the pupil smaller and focus on objects. This widens (dilates) the pupil. The medication also relaxes the eye muscle that helps you focus on nearby objects, making it harder to see up close.

Drug Facts

Common BrandsIsopto Atropine
Drug ClassAnticholinergic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Atropine (Isopto Atropine)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

  • Drowsiness
  • Feeling restless
  • Feeling irritable
  • Dry mouth
  • Dry skin
  • Flushed skin on face or neck
  • Rash
  • Fast heart rate

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe allergic reaction: swollen eyelid, inflamed skin, red or itchy eyes, shortness of breath
  • Too much atropine in the body: dry skin, flush skin, rapid pulse, delirium, changes in behavior

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Symptoms of too much medicine being absorbed into the body

Clumsiness or unsteadiness

confusion or unusual behavior

dryness of skin

fast or irregular heartbeat

fever

flushing or redness of face

seeing, hearing, or feeling things that are not there

skin rash

slurred speech

swollen stomach in infants

thirst or unusual dryness of mouth

unusual drowsiness, tiredness, or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Blurred vision

brief burning or stinging of the eyes

eye irritation not present before use of this medicine

increased sensitivity of eyes to light

swelling of the eyelids

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Atropine (Isopto Atropine)

thumbs-up

Pros

Eye drops can be used in children 3 months and older

Can be used as an alternative to wearing a patch over the stronger eye for treating lazy eye

thumbs-down

Cons

Can make your eyes sensitive to light and vision blurry for up to 2 weeks

Might raise your blood pressure

pharmacist-tips

Pharmacist tips for Atropine (Isopto Atropine)

pharmacist
  • For use during routine eye exams: You'll typically get atropine (Isopto Atropine) placed in the eye(s) at the eye specialist's office during a routine eye exam. After your appointment, consider wearing sunglasses when you go outside since your pupils might still be dilated and your eyes will be sensitive to light. It might be a good idea to have someone drive you to and from your eye appointment.

    • For use at home for lazy eye: Follow the eye specialist's instructions when you or your child uses atropine (Isopto Atropine) at home for treating lazy eye. This makes sure you use the medication safely. Wash your hands with soap and water before and after you use the medication to prevent it from getting into the mouth.

      • Atropine (Isopto Atropine) can blur your vision and cause light sensitivity, sometimes lasting a couple weeks. Some people might also feel drowsy after they use this medication. Don't drive a car or operate machinery until you know how this medication affects you.

        • Don't let the tip of the tube or eye drop bottle touch the eye, eyelid, fingers, or other surfaces. Otherwise, atropine (Isopto Atropine) can get contaminated with germs and cause serious harm to the eye, like infection and vision loss.

          • If you wear contact lenses, make sure to take them out before you place atropine (Isopto Atropine) into the eye. The eye drops contain a preservative that can damage your lenses. Wait at least 15 minutes after you place the medication in your eye before putting your lenses back in. Check with your eye specialist about using contact lenses during treatment with atropine (Isopto Atropine).

            • While looking up, pull down your lower eyelid with one hand and hold the eye drop bottle upside down above your eye. Then, squeeze the number of drops you need for your dose.

              • After you place the drop(s) in your eye, close your eye for 2 to 3 minutes. Press down on the inner corner of your eye near your nose with your finger for a minute to keep the medication in your eye and prevent it from leaking. Wipe away any extra medication from your face with a clean, dry tissue.

                • If you need to use another eye drop medication with atropine (Isopto Atropine) in the same eye, wait at least 5 minutes so the second eye drop doesn't rinse off the first one.

                  • First, tilt your head back slightly. Then, pull down your lower eyelid with one hand and hold the tube of ointment with the other. Place a half-inch strip of ointment in the space between your eyelid and eye.

                    • After you place the ointment into the eye, gently blink and then close your eye for 1 to 2 minutes to help the medication reach all the necessary parts of the eye. Press down on the inner corner of your eye near your nose with your finger for 2 to 3 minutes so the medication stays in your eye.

                      Tips for giving the atropine (Isopto Atropine) eye drops or eye ointment to children:

                      • Have your child lie down on their back on a flat surface. Ask them to tilt their head up and to look up. Then, rest the wrist of the hand that's holding atropine (Isopto Atropine) on your child's forehead.

                        • Pull down your child's lower eyelid with your other hand, and apply the medication along the lower eyelid away from the inner corner near the nose. Afterwards, ask your child to close or blink their eyes for a minute to spread the medication throughout the eye.

                          faqs

                          Frequently asked questions about Atropine (Isopto Atropine)

                          Can I buy atropine (Isopto Atropine) eye drops over the counter?
                          No, atropine (Isopto Atropine) eye drops aren't available over the counter. You'll need a prescription for it from a healthcare professional. For routine eye exams, your eye specialist will place atropine (Isopto Atropine) eye drops into your eye(s) at their office to dilate your pupil and check the health of your eye(s).
                          How long does atropine (Isopto Atropine) last?
                          Atropine (Isopto Atropine) dilates or widens the pupil. This effect can sometimes last several days. Since widening the pupil causes blurry vision, your vision might be affected for several days as well. Be careful doing anything that you need clear, sharp vision for. Make sure your vision is clear before driving or operating heavy machinery. Speak with the eye specialist if you're concerned about how long the effects of the medication lasts.
                          What are the long-term side effects of atropine (Isopto Atropine) eye drops?
                          Most side effects from atropine (Isopto Atropine) are temporary. Common side effects of the medication include temporary eye pain and stinging when it's placed into the eye. Other common side effects, such as blurry vision and light sensitivity, might last up to 2 weeks after you put the medication into the eye. Make sure to avoid driving a car or operating machinery until your vision is fully back to normal. Talk with an eye specialist if you're concerned about side effects from atropine (Isopto Atropine).
                          How long can you use atropine (Isopto Atropine) eye drops?
                          How long you use atropine (Isopto Atropine) depends on the reason you need the medication and your eye specialist's directions. For eye exams, atropine (Isopto Atropine) is usually used only during the appointment. But for treating lazy eye, it can take an average of 4 months of treatment to see improvement. Make sure you don't use atropine (Isopto Atropine) more often or longer than what your treatment requires. Otherwise, it can raise your risk of side effects.
                          Why is atropine (Isopto Atropine) used after eye surgery?
                          Atropine (Isopto Atropine) is often used after eye surgery to lessen eye inflammation. It's also thought to lessen the risk for complications after surgery, such as fluid buildup in the eye. This is an off-label use of the medication. So the eye specialist will weigh the benefits of using atropine (Isopto Atropine) after eye surgery and the risks for side effects affecting vision to decide whether this medication is right for you.
                          Are atropine (Isopto Atropine) eye drops for myopia or nearsightedness?
                          There are mixed findings from studies about using atropine (Isopto Atropine) eye drops for myopia (nearsightedness) in children. One study showed that low-dose atropine (Isopto Atropine) eye drops might help slow down myopia in children when used regularly at bedtime. But another study's findings don't support this. Keep in mind that dose of atropine (Isopto Atropine) used in these myopia studies is much lower than what's commercially available. Using atropine (Isopto Atropine) eye drops for this purpose is considered off-label because the medication is FDA approved only to dilate the pupil and treat lazy eye. More research is still needed to make sure atropine (Isopto Atropine) is safe and works well for nearsightedness in children. Talk to your eye specialist for the best treatment for nearsightedness.
                          Can atropine (Isopto Atropine) eye drops be given sublingually or orally?
                          Don't take or give atropine (Isopto Atropine) eye drops sublingually (under the tongue) or orally (swallowed) unless specifically instructed by the prescriber. Atropine (Isopto Atropine) eye drops are only FDA approved to use in the eyes. There's limited evidence that the off-label usage of the eye drops given sublingually might be helpful for certain people who have severe drooling due to a problem related to the nervous system. But more research is needed in this area. Keep in mind that taking atropine (Isopto Atropine) eye drops by mouth might lead to having too much atropine in the body (atropine poisoning), which can be life-threatening. Follow your prescriber's instructions on how to use atropine (Isopto Atropine) eye drops for your particular medical condition.
                          What's the difference between Isopto Atropine and Isopto Carpine?
                          Isopto Atropine is the brand name for atropine eye drops. Isopto Carpine is the brand name for pilocarpine eye drops. The brand name Isopto Carpine is no longer available, so only generic pilocarpine eye drops are available. These two eye drop medications have very different uses. Atropine (Isopto Atropine) is used to dilate the pupil, whereas pilocarpine eye drops are used to shrink the pupil. Both eye drops can affect your vision, so avoid driving or using heavy machinery until your vision completely goes back to normal. Ask an eye specialist if you have other questions about comparing between the two medications.
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                          What are the risks and warnings for Atropine (Isopto Atropine)?

                          Atropine (Isopto Atropine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                          risk-warning

                          Light sensitivity and blurry vision

                          Atropine (Isopto Atropine) can cause blurry vision. It can also make your eyes be more sensitive to light (squinting or eye discomfort when there's light). These side effects might last up to 2 weeks after you use the eye medication. Consider wearing sunglasses when you step outside after you use atropine (Isopto Atropine). Don't drive a car or operate machinery until you know how the medication affects your vision.

                          risk-warning

                          Rise in blood pressure

                          Atropine (Isopto Atropine) might raise your blood pressure. Talk to your healthcare team if you have a history of high blood pressure or are concerned about this possible effect. Your eye specialist might recommend that you check your blood pressure at home if you're using atropine (Isopto Atropine) to treat lazy eye.

                          risk-warning

                          Greater risk of side effects in people with certain medical conditions affecting the nervous system

                          • Risk factors: Down syndrome | Spastic paralysis | Brain damage

                            Some people who have had brain damage, have Down syndrome, or have a nerve problem that causes paralysis are at a greater risk of serious side effects from atropine (Isopto Atropine). It can cause damage to their brain function, heart, lungs, or digestive system. Make sure your care team knows your medical history before you start this medication.

                            dosage

                            Atropine (Isopto Atropine) dosage forms

                            The average cost for 1 eye dropper of 5ml of 1% of Atropine (Isopto Atropine) is $26.50 with a free GoodRx coupon. This is 59.76% off the average retail price of $65.85.
                            eye dropper
                            Eye dropper
                            DosageQuantityPrice as low asPrice per unit
                            2ml of 1%1 eye dropper$16.11$16.11
                            5ml of 1%1 eye dropper$26.50$26.50
                            15ml of 1%1 eye dropper$50.59$50.59

                            Typical dosing for Atropine (Isopto Atropine)

                            • Eye drops

                              • People 3 months and older: The typical dose is 1 drop in the affected eye(s) 40 minutes before the dilation time.

                              • People 3 years and older: The typical dose is 1 drop in the affected eye(s) 40 minutes before the dilation time. The dose can be repeated up to 2 times daily as directed by the eye specialist.

                            • Eye ointment

                              • The typical dose is to put about a half-inch strip of ointment in the affected eye(s) 1 or 2 times daily, or as directed by the eye specialist.

                            interactions

                            Interactions between Atropine (Isopto Atropine) and other drugs

                            Atropine (Isopto Atropine) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Atropine (Isopto Atropine). Please note that only the generic name of each medication is listed below.

                            Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

                            Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

                            Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                            drug-cost

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                            contraindications-icon

                            Atropine (Isopto Atropine) contraindications

                            Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Atropine (Isopto Atropine) will not be safe for you to take.
                            alternatives

                            What are alternatives to Atropine (Isopto Atropine)?

                            There are a number of medications that your doctor can prescribe in place of Atropine (Isopto Atropine). Compare a few possible alternatives below.
                            Atropine (Isopto Atropine)
                            Used for:
                            • Pupil dilation (e.g., for eye exams) - eye drops and eye ointment

                            • Temporary paralysis of the eye muscle (cycloplegia) - eye drops and eye ointment

                            • Treatment for lazy eye - eye drops only

                            $16.11 Lowest GoodRx priceView Prices
                            Used for:
                            • Pupil dilation

                            $44.82 Lowest GoodRx priceView Prices
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                            Atropine (Isopto Atropine) images

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                            References

                            Best studies we found
                            View All References (12)

                            Ferris, J. D. (2015). Amblyopia: Atropine. American Academy of Ophthalmology. 

                            Healthychildren.org. (2013). How to give eye drops and eye ointment.

                            Laspas, P., et al. (2023). Effects of postoperative atropine eye drops on visual quality in patients undergoing trabeculectomy. Journal of Clinical Medicine.

                            Michelon, H., et al. (2021). Atropine-induced toxicity after off-label sublingual administration of eyedrop for sialorrhoea treatment in neurological disabled patients. British Journal of Clinical Pharmacology.

                            National Eye Institute. (2024). Types of glaucoma.

                            Oltra, E. (2015). Amblyopia treatment modalities. American Academy of Ophthalmology.

                            Raschka, M., et al. (2023). Ophthalmic atropine: A typical anticholinergic toxidrome from an atypical old culprit. The Journal of Pediatric Pharmacology and Therapeutics.

                            Repka, M. X., et al. (2023). Low-dose 0.01% atropine eye drops vs placebo for myopia control: A randomized clinical trial. Journal of the American Medical Association Ophthalmology.

                            SafeMedication. (n.d.). How to use eye drops.

                            SafeMedication. (n.d.). How to use eye ointments and gels.

                            Somerset Therapeutics, LLC. (2024). Atropine sulfate- atropine sulfate monohydrate solution/ drops [package insert]. DailyMed.

                            Stellpflug, S. J., et al. (2012). Massive atropine eye drop ingestion treated with high-dose physostigmine to avoid intubation. The Western Journal of Emergency Medicine.

                            GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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