Atacand HCT is a combination medication used to lower high blood pressure in adults. It contains candesartan (an angiotensin II receptor blocker, or ARB) and hydrochlorothiazide (a thiazide diuretic). This medication comes as a tablet that's taken by mouth, typically once per day. Side effects aren't common, but can include upper respiratory tract infection and dizziness. Atacand HCT (candesartan / hydrochlorothiazide) is available as brand name and generic medications.
Atacand HCT is a combination of two medications that help lower blood pressure in different ways:
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
dizziness
dryness of the mouth
increased thirst
irregular heartbeat
lightheadedness
muscle cramps
unusual tiredness
vomiting
weak pulse
weakness
Rare
Arm pain
chest pain or tightness
fast heartbeat
large, hive like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
trouble breathing
Incidence not known
Black, tarry stools
chills
confusion
lower back or side pain
nervousness
numbness or tingling in the hands, feet, or lips
painful or difficult urination
pale skin
persistent non-healing sore
pink growth
reddish patch or irritated area
shiny bump
sores, ulcers, or white spots in the mouth or on the lips
stomach pain
swelling of the face, ankles, or hands
unusual bleeding or bruising
weakness or heaviness of the legs
white, yellow or waxy scar-like area
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Back pain
headache
joint pain
loss of appetite
muscle aches and pains
sweating
trouble sleeping
Incidence not known
Blistering, peeling, loosening of skin
decreased interest in sexual intercourse
hair loss, thinning of the hair
hives or welts, itching, skin rash
inability to have or keep an erection
increased sensitivity of the skin to sunlight
loss in sexual ability, desire, drive, or performance
redness of the skin
redness or other discoloration of the skin
red irritated eyes
red skin lesions, often with a purple center
severe sunburn
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
In general, side effects aren't very common with Candesartan/HCTZ. The most commonly reported side effect in clinical studies was upper respiratory tract infections, such as the common cold. This is a typical side effect of ARBs like candesartan in Atacand HCT. Another side effect to look for is dizziness. Dizziness can happen as Candesartan/HCTZ works to lower your blood pressure. If you experience dizziness, it should get better as you continue to take the medication and your body gets used to your new blood pressure.
Hair loss wasn't a reported side effect in people taking Candesartan/HCTZ during clinical studies. However, there were some reports of hair loss after Candesartan/HCTZ was released into the market. But it's unclear whether the hair loss was caused by Candesartan/HCTZ or other factors. If you notice hair loss while you're taking Candesartan/HCTZ, contact a healthcare professional so they can help you figure out what might be the cause.
Constipation isn't a common side effect of Candesartan/HCTZ. However, constipation is a potential symptom of dehydration, which is possible from hydrochlorothiazide in Atacand HCT since it's a water pill. Contact your prescriber if you experience constipation. They might recommend drinking more water to stay hydrated or using a laxative that's appropriate for you.
No, Candesartan/HCTZ doesn't typically cause dry mouth. But because Atacand HCT contains a diuretic (water pill), you're at risk for becoming dehydrated if you're not drinking enough water or if you're losing body fluids through vomiting or diarrhea. Some people can experience dry mouth if they become dehydrated because the body produces less saliva. If you have dry mouth, let your healthcare team know. They can check to see if you're dehydrated and need more medical attention. Or, they might recommend ways to ease your symptoms, such as drinking more water or using saliva substitutes.
There aren't any specific foods that are known to interact with Candesartan/HCTZ. But if you have high blood pressure, you should eat a nutritious meal that's low in salt to help your condition. It's best to avoid or limit canned foods, processed foods, or pickled foods because these are typically high in salt content.
No, don't take Atacand HCT if you're pregnant. This medication contains candesartan, which is an ARB. Taking an ARM during pregnancy can cause harm to unborn babies. Tell your prescriber right away if you're pregnant or thinking of becoming pregnant because they'll need to switch you to a safer option.
Yes, Candesartan/HCTZ is available as a generic.
Atacand HCT (candesartan / hydrochlorothiazide) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Don't take Atacand HCT (candesartan / hydrochlorothiazide) if you're pregnant. Candesartan in Atacand HCT can cause severe and sometimes life-threatening harm to unborn babies. If you find out that you're pregnant, stop taking this medication and let your prescriber know right away. If you're pregnant before starting Atacand HCT (candesartan / hydrochlorothiazide) or thinking of becoming pregnant during treatment, discuss with your healthcare professional (HCP) about safer options to treat your blood pressure.
Atacand HCT (candesartan / hydrochlorothiazide) can cause your blood pressure to drop too much, which can make you feel dizzy, tired, or lightheaded. This side effect is more common if you're dehydrated from diarrhea or vomiting, or if you have heart failure. Before you start Atacand HCT (candesartan / hydrochlorothiazide), your care team will check to see if your fluid and salt levels are balanced. They will instruct you to stay well-hydrated to avoid having blood pressure that's too low. Sit down slowly while holding onto something if you feel dizzy from low blood pressure. Let your care team know if your blood pressure drops too much. Get medical help immediately if you fall and hit your head.
In general, ARBs like candesartan in Atacand HCT can protect the kidneys. But in some cases, they might also cause kidney injury. For example, ARBs might cause harm in people with severe heart failure, a kidney condition called renal artery stenosis (RAS), or are dehydrated. Let your prescriber know if you're having problems with urination, as this could be a sign that your kidneys aren't working as well.
Atacand HCT (candesartan / hydrochlorothiazide) can affect the level of certain electrolytes, including sodium, potassium, and magnesium in your body. It can also change your blood sugar levels and raise the cholesterol and triglycerides levels.
You might need regular blood tests done while taking Atacand HCT (candesartan / hydrochlorothiazide) to check that your electrolyte, blood sugar, and cholesterol levels are within a safe range. Let your care team know about all the medications you're taking because some of them can cause similar changes. Also, tell your care team if you experience an irregular heartbeat, weakness, low energy, muscle weakness or cramps, reduced urination, nausea, or vomiting. These can be signs of electrolyte imbalances.
Atacand HCT (candesartan / hydrochlorothiazide) can cause allergic reactions. Your risk is higher if you have a history of allergies, asthma, or a sulfa allergy, though it can happen to anyone. Let your prescriber know if you have a rash, itchiness, hives, trouble breathing, or swelling in the face.
Although rare, some people experience vision changes or eye pain within hours or weeks of starting taking hydrochlorothiazide, an ingredient in Atacand HCT. Tell your prescriber right away about any vision changes and stop taking Atacand HCT (candesartan / hydrochlorothiazide), as untreated symptoms could lead to permanent vision loss.
Medications containing hydrochlorothiazide like Atacand HCT can cause or worsen lupus. Talk to your prescriber if you have symptoms such as feeling very tired, joint pain, or a skin rash across your cheeks and nose.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 16mg/12.5mg | 90 tablets | $69.27 | $0.77 |
| 32mg/12.5mg | 90 tablets | $90.84 | $1.01 |
| 32mg/25mg | 90 tablets | $109.81 | $1.22 |
Your prescriber will determine your dose based on different factors like how high your blood pressure is and the dosages of any blood pressure medications you're currently taking.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Atacand HCT (candesartan / hydrochlorothiazide) will not be safe for you to take.