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Zynteglo

Zynteglo Side Effects

Kristianne Hannemann, PharmDAllison Gourley, PharmD
Reviewed by Kristianne Hannemann, PharmD, Allison Gourley, PharmD
Last reviewed on August 25, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Mouth or gut inflammation (swelling/irritation) (95%)
  • Fever during low white blood cell count (51%)
  • Fever (49%)
  • Vomiting (49%)
  • Hair loss (44%)
  • Nose bleed (42%)
  • Stomach pain (39%)
  • Muscle and bone pain (37%)
  • Cough (34%)

Less Common Side Effects

  • Headache
  • Rash
  • Diarrhea
  • Nausea
  • Constipation
  • Low appetite
  • Skin color changes

Zynteglo serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: trouble breathing, rash, swelling of lips, tongue, or throat
  • Severe bleeding: stomach cramps, red or tarry stool, blood in the urine, any bleeding that's difficult to stop, tiredness, weakness
  • Serious infection: fever, cough, sore throat, tiredness, chills, body aches

Source: FDA

The following Zynteglo side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
  • Infection—fever, chills, cough, or sore throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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