The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Mouth or gut inflammation (swelling/irritation) (95%)
- Fever during low white blood cell count (51%)
- Fever (49%)
- Vomiting (49%)
- Hair loss (44%)
- Nose bleed (42%)
- Stomach pain (39%)
- Muscle and bone pain (37%)
- Cough (34%)
Less Common Side Effects
- Headache
- Rash
- Diarrhea
- Nausea
- Constipation
- Low appetite
- Skin color changes
Zynteglo serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: trouble breathing, rash, swelling of lips, tongue, or throat
- Severe bleeding: stomach cramps, red or tarry stool, blood in the urine, any bleeding that's difficult to stop, tiredness, weakness
- Serious infection: fever, cough, sore throat, tiredness, chills, body aches
Source: FDA
The following Zynteglo side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Infection—fever, chills, cough, or sore throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

