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Zestoretic

Zestoretic Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on August 2, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dizziness (8%)
  • Headache (5%)
  • Cough (4%)
  • Extreme tiredness (4%)
  • Feeling lightheaded when standing after sitting or lying down (3%)

Less Common Side Effects

  • Chest pain
  • Stomach cramps
  • Constipation
  • Dry mouth
  • Muscle cramps
  • Lower sex drive
  • Ringing in the ear

Zestoretic serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Angioedema (severe swelling): swelling of the face, arms or legs, lips, tongue, or throat
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint
  • Serious kidney problems: urinating less often than usual, swelling in your feet, ankles, or hands, unexplained weight gain
  • Liver problems: yellowing of the skin or eyes, stomach pain, nausea, vomiting, confusion
  • High blood potassium levels: nausea, muscle weakness, abnormal heartbeat
  • Severe allergic reaction: swelling of your lips, tongue, throat, or face, trouble breathing, rash

Source: DailyMed

The following Zestoretic side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blurred vision

body aches or pain

chills

confusion

cough

diarrhea

difficulty breathing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

ear congestion

fever

headache

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of voice

nausea

runny or stuffy nose

sneezing

sore throat

sweating

unusual tiredness or weakness

vomiting

Incidence not known

Persistent non-healing sore

pink growth

reddish patch or irritated area

shiny bump

white, yellow or waxy scar-like area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Belching

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

decreased interest in sexual intercourse

feeling of constant movement of self or surroundings

heartburn

inability to have or keep an erection

indigestion

lack or loss of strength

loss in sexual ability, desire, drive, or performance

muscle cramps

rash

sensation of spinning

sleepiness or unusual drowsiness

stomach discomfort, upset, or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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