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Fosinopril/HCTZ

Fosinopril/HCTZ Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on January 21, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (7%)
  • Cough (6%)
  • Tiredness (4%)
  • Dizziness (3%)
  • Upper respiratory infection (e.g., common cold; 2%)
  • Muscle, bone, or joint pain (2%)

Less Common Side Effects

  • Gout
  • Dry mouth
  • Weakness
  • Swelling of the hands or ankles
  • Flushing
  • Nausea or vomiting
  • Diarrhea
  • Indigestion or heartburn
  • Stomach pain
  • Feeling the need to urinate more often
  • Electrolyte disturbances

Fosinopril/HCTZ serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Angioedema (severe swelling): swelling of the face, arms or legs, lips, tongue, or throat
  • Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing, skin reddening
  • Low blood pressure: dizziness, tiredness, feeling faint, confusion
  • Kidney problems: urinating less often than usual
  • Liver problems: yellowing of the skin or eyes, stomach pain, nausea, vomiting, confusion

Source: DailyMed

The following Fosinopril/HCTZ side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blurred vision

chest pain or discomfort

chills

cold sweats

confusion

decreased urination

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

dry mouth

fainting

fast, slow, or irregular heartbeat

muscle cramps or pain

numbness, tingling, pain, or weakness in the hands or feet

rapid breathing

seizures

sunken eyes

sweating

thirst

trembling

unusual tiredness or weakness

weakness and heaviness of legs

wrinkled skin

Incidence not known

Persistent non-healing sore

pink growth

reddish patch or irritated area

shiny bump

white, yellow or waxy scar-like area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Cough

Less common

Body aches or pain

diarrhea

difficult breathing

ear congestion

fever

headache

loss of voice

muscle or bone pain

nausea and vomiting

runny or stuffy nose

sneezing

sore throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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