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If you smoke cigarettes, using combined oral contraceptives (COCs), like Yasmin, raises your risk for serious health problems, such as strokes, heart attacks, and blood clots. Females ages 35 years and older who smoke are at even higher risk for these problems. If you smoke, talk with your provider about safer birth control alternatives.

Yasmin raises your risk of blood clots. These clots can occur anywhere in your body, including your lungs (pulmonary embolism or PE), legs (deep vein thrombosis or DVT), brain (stroke), and heart (heart attack). Get emergency help right away if you have any signs of a blood clot:

Study results are mixed, but there's a possibility that Yasmin and other COCs can raise your risk for breast and cervical cancer.

Though rare, Yasmin can cause liver problems, such as liver damage and liver tumors. These problems are linked more with earlier formulations of COCs that contained higher levels of estrogen (50 mcg or higher), and less so with Yasmin since it only contains 30 mcg of estrogen. Don't use this medication if you already have liver problems. Call your provider right away if you experience symptoms of liver problems, such as tiredness, stomach pain, or yellowing of the skin or whites of the eyes.

Yasmin and other COCs can raise your blood pressure. Your provider might ask you to check your blood pressure regularly. If you notice your blood pressure is higher while you're taking this medication, contact your provider. If you have uncontrolled high blood pressure, Yasmin might not be the best option for you.

COCs like Yasmin might raise your blood sugar and triglyceride (fat) levels. In addition, some progesterones could raise LDL levels ("bad" cholesterol). If you have diabetes, let your provider know if you experience any changes in your blood sugar. If your lipids aren't under control, you might need to use a different form of birth control. Make sure to go to all of your check-ups so your provider can monitor any changes.

Headaches are a common side effect of COCs like Yasmin. But, if you experience a new migraine, a migraine that's worse than normal, or a new headache that keeps coming back or is severe, call your provider so you can be checked out.

Let your provider know if you experience symptoms of depression or worsening depression while taking Yasmin. In cases of serious depression, your provider might have you stop taking it.

Certain medications can make Yasmin get broken down faster in your body, making it less effective (not work as well). This can lead to pregnancy. Some examples include carbamazepine (Tegretol) and phenytoin (Dilantin). Use a back-up method or other form of birth control for at least 28 days after stopping any of these medications. Other medications can raise the amount of Yasmin in your body, which can lead to more side effects. Make sure to tell your provider or pharmacist all of your medications so they can make sure they don't interact with Yasmin.

Yasmin contains drospirenone, which can cause high levels of potassium in some people. Taking Yasmin with medications that raise potassium levels like ACE inhibitors, potassium-sparing diuretics, or potassium supplements can put you more at risk. Your provider should monitor your potassium levels during your first cycle of Yasmin and periodically while taking this medication.