The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Muscle or joint pain (up to 38%)
- Higher liver enzyme levels in the blood (up to 36%)
- Neutropenic fever (low white blood cells with fever; up to 27%)
- Tiredness (up to 24%)
- Constipation (up to 20%)
- Swelling (up to 20%)
- Mouth sores (up to 20%)
Less Common Side Effects
- Nausea
- Diarrhea
- Fever
- Dizziness
- Headache
- Rash
Xospata serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Differentiation syndrome: fever, sudden weight gain, trouble breathing, chest pain, swelling in legs
- Nervous system problems: vision changes, confusion, seizures, loss of consciousness
- Changes in heart rhythm: lightheadedness, irregular heartbeat, blurry vision, fainting, loss of consciousness, seizures
Source: DailyMed
The following Xospata side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Fever, cough, dizziness, feeling faint or lightheaded, shortness of breath, bone pain, sudden weight gain, swelling of the ankles, hands, or feet, which may be signs of differentiation syndrome
- Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
- Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
- Sudden and severe headache, confusion, change in vision, seizures, which may be signs of posterior reversible encephalopathy syndrome (PRES)
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Bone, joint, or muscle pain
- Constipation
- Diarrhea
- Dizziness
- General discomfort and fatigue
- Pain, redness, or swelling with sores inside the mouth or throat
- Nausea
