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Xhance (fluticasone) is a corticosteroid used to treat chronic rhinosinusitis, with or without nasal polyps, in patients 18 years of age or older. It is less popular than other comparable drugs. There are currently no generic alternatives to Xhance.
GoodRx has partnered with InsideRx and OptiNose to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Xhance is covered by some Medicare and insurance plans.
Get Xhance for as low as $595.47, which is 25% off the average retail price of $792.45 for the most common version, by using a GoodRx coupon.

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GoodRx coupon prices last updated on 02/15/26.
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