The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
VHL disease:
- Low red blood cell count (93%)
- Tiredness (64%)
- Rise in creatinine (64%)
- Headache (39%)
- Dizziness (38%)
- Rise in blood sugar (34%)
- Nausea (31%)
Advanced kidney cancer:
- Low red blood cell count (88%)
- Tiredness (43%)
- Muscle or bone pain (34%)
- Low white blood cell counts (34%)
- Rise in creatinine (up to 34%)
- Lower sodium levels (31%)
- Higher potassium levels (29%)
- Rise in liver enzymes (27%)
Adrenal or nerve tumor:
- Low red blood cell count (96%)
- Tiredness (56%)
- Muscle and bone pain (56%)
- Low white blood cells (up to 54%)
- Rise in liver enzymes (up to 51%)
- Higher calcium levels (34%)
- Shortness of breath (33%)
- Higher potassium levels (31%)
- Headache (29%)
- Dizziness (26%)
- Nausea (25%)
Less Common Side Effects
VHL disease:
- Vision problems
- Infections
- Shortness of breath
- Rise in liver enzymes
- Muscle pain
- Joint pain
- Stomach pain
- Constipation
Advanced kidney cancer:
- Swelling
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Stomach pain
- Shortness of breath
- Reduced appetite
- Headache
- Dizziness
Adrenal or nerve tumor:
- Swelling
- Muscle spasms or weakness
- Cough
- Stuffy nose
- Constipation
- Diarrhea
- Stomach pain
- Vomiting
- Bleeding
- Reduced appetite
- Weight gain
- Lower sodium levels
- Lower platelet count
Welireg serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Low red blood cell count (anemia): tiredness, feeling cold, shortness of breath, chest pain, fast heartbeat
- Low oxygen levels: shortness of breath, fast heartbeat
Source: DailyMed
The following Welireg side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Shortness of breath or trouble breathing
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Fatigue
- Joint pain
- Muscle pain
