Medications for Eczema (Atopic Dermatitis): What Are the Options?

For some people with eczema, a chronic skin condition marked by dry, itchy skin and rashes, lifestyle changes may be enough to keep symptoms under control. Others, however, may need medications to keep eczema at bay.

“If your symptoms are persisting, you may need medications, which means speaking to your dermatologist, and potentially getting a prescription,” says Nkem Ugonabo, MD, Dermatologist in New York City.

What are medication options for eczema?

For people whose eczema can’t be managed by moisturizers and other lifestyle changes, here are some of the medications that can help:

Topical steroids

These come in the form of creams or ointments that can be applied to rashes once or twice a day to relieve symptoms and calm down flares. They come in varying strengths, with stronger versions only available via a prescription. 

Oral antihistamines

These are available both over the counter and by prescription. Your provider may recommend them if your itchiness is severe and affecting your quality of life.

Biologic therapy

These are injectable medications that are used to treat more severe cases of eczema. They act on parts of your immune system that are linked to eczema activity, and are only available via prescription.

Note that there are other medication options that may help with eczema, and your provider can give you a more comprehensive list based on your personal factors.

How do you choose an eczema medication?

Keep in mind that it may take some time to find the right treatment for your eczema, because each medication affects people in different ways. Being open and honest with your provider may help them find the right treatment plan for you.