The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low white blood cell counts (up to 73%)
- Rash (36%)
- Headache (11%)
Less Common Side Effects
- Nausea
- Diarrhea
- Inflammation of nose and throat (e.g., runny or stuffy nose, scratchy throat)
- Higher liver enzyme levels
Note: Side effects were from people 8 years and up. Side effects were similar for children 1 to 8 years of age.
Tzield serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Epstein-Barr virus (EBV) or cytomegalovirus (CMV): tiredness, fever, sore throat, swollen lymph nodes in the neck, rash, yellow skin or eyes
- Other infection: fever, trouble breathing, cough, weakness, sweating, chills, diarrhea, stomach pain
- Cytokine release syndrome (CRS): fever, nausea, tiredness, headache, muscle or joint pain
- Allergic reaction: facial or throat swelling, trouble breathing, hives, rash, vomiting, fever
When do Tzield possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Low white blood cell count
Risk of cytokine release syndrome (CRS)
Seek immediate medical care if you experience this side effect.
Source: Prescribing information
The following Tzield side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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