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Tri-Luma (Flucinolone/Hydroquinone/Tretinoin) is a combination corticosteroid, a retinoid similar to vitamin A, and a drug used to lighten the skin. It is used on the skin to treat melasma. Tri-Luma is the most popular melanin synthesis inhibitor/retinoid/corticosteroid combinations. There are currently no generic alternatives to Tri-Luma.
GoodRx has partnered with InsideRx and Galderma Pharmaceuticals to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Tri-Luma is covered by
most Medicare and insurance plans.
With the Patient Assistance Program from PAN Foundation, contact the program to see how they can financially help you out.


| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 30g of 0.05% | 1 tube | $294.85 | $207.30 |
GoodRx coupon prices last updated on 04/11/26.
*Prices subject to change without notice. Sales tax may apply and is not included.