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Tri-Luma (Flucinolone/Hydroquinone/Tretinoin) is a combination corticosteroid, a retinoid similar to vitamin A, and a drug used to lighten the skin. It is used on the skin to treat melasma. Tri-Luma is the most popular melanin synthesis inhibitor/retinoid/corticosteroid combinations. There are currently no generic alternatives to Tri-Luma.
GoodRx has partnered with InsideRx and Galderma Pharmaceuticals to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Tri-Luma is covered by
most Medicare and insurance plans.
With the Patient Assistance Program from PAN Foundation, contact the program to see how they can financially help you out.
You can save more on select medications with GoodRx Companion. See which medications are eligible.

| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 30g of 0.05% | 1 tube | $294.51 | $227.92 |
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GoodRx coupon prices last updated on 09/22/26.