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Trelegy Ellipta

How Much Is Trelegy Ellipta Without Insurance?

Tamara E. HolmesJoshua Murdock, PharmD, BCBBS
Written by Tamara E. Holmes, Cindy George, MPH | Reviewed by Joshua Murdock, PharmD, BCBBS
Updated on May 18, 2026

Key takeaways:

  • Trelegy Ellipta (fluticasone furoate / umeclidinium / vilanterol) contains three active ingredients that decrease inflammation and relax air passages in the lungs. The inhaler is used for the long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma.

  • If you don’t have insurance, the amount you’ll pay for Trelegy Ellipta depends on factors such as where you live, your pharmacy, and whether you qualify for any discounts or coupons. The average cost of one 100 mcg / 62.5 mcg / 25 mcg Trelegy Ellipta inhaler is about $844.16 without insurance.

  • You may be able to pay less for Trelegy Ellipta by using a GoodRx coupon or comparing prices at different pharmacies. If you’re eligible, you also may be able to save by using a manufacturer copay savings card or patient assistance program.

Save on related medications

Having asthma or chronic obstructive pulmonary disease (COPD) can make breathing difficult, and for some people, lead to a poor quality of life. Trelegy Ellipta is a brand-name, once-daily inhaler that can help make it easier for people with these conditions to breathe. 

Trelegy Ellipta contains three active ingredients: fluticasone furoate, umeclidinium, and vilanterol. Fluticasone decreases inflammation in the lungs, while umeclidinium and vilanterol relax the airways in the lungs. Trelegy Ellipta isn’t a rescue inhaler, so it won’t relieve sudden or emergency breathing problems. Instead, it can offer relief over time as a maintenance treatment.

Convenience can sometimes come at a cost, though. Because Trelegy Ellipta combines three medications into one inhaler and doesn’t yet have a generic version, what you pay at the pharmacy may be higher than you’d like. But there are still ways to save.

Trelegy Ellipta basics

The chart below provides a summary of basic information about Trelegy Ellipta.

Brand name Trelegy Ellipta
Generic name No generic available
Available doses
  • 100 mcg / 62.5 mcg / 25 mcg
  • 200 mcg / 62.5 mcg / 25 mcg
Recommended dosages
  • Asthma: One 100 mcg / 62.5 mcg / 25 mcg inhalation or one 200 mcg / 62.5 mcg / 25 mcg inhalation at the same time every day
  • COPD: One 100 mcg / 62.5 mcg / 25 mcg inhalation at the same time every day
FDA-approved uses
  • Long-term treatment of asthma in adults
  • Long-term treatment of COPD in adults

How much does Trelegy Ellipta cost without insurance?

As of January 2026, Trelegy Ellipta’s manufacturer list price is about $698 for one inhaler. But the price you actually pay may be different because of potential wholesaler and pharmacy markups. Your dosage and where you live can also play a role.

The table below shows the average retail prices for different doses of Trelegy Ellipta.

Dosage form

Trelegy average cash price

One 100 mcg / 62.5 mcg / 25 mcg inhaler

$844.16

One 200 mcg / 62.5 mcg / 25 mcg inhaler

$857.81

Is Trelegy Ellipta covered by insurance?

Many health insurance plans cover Trelegy Ellipta. But coverage varies by plan. If you have insurance, check your plan’s summary of benefits and coverage and formulary to determine whether Trelegy Ellipta is covered. While you’re doing this, you can also figure out if you’ll need to get a prior authorization or do step therapy.

If your insurance doesn’t cover Trelegy Ellipta, here are a few options to try:

  • Talk to your prescriber about alternative medications.

  • Ask for a formulary exception from your insurance plan.

  • If you request a formulary exception and it’s denied, file an appeal with your plan.

  • Consider changing your prescription medication coverage during your next open enrollment period.

  • Check if you’re eligible for savings through GSK’s patient assistance program for people without insurance. Or if you have commercial insurance, see if you qualify for a copay savings card.

Ways to save on Trelegy Ellipta

Below are six potential ways to save on Trelegy Ellipta, with or without insurance.

1. Use a GoodRx coupon

With a GoodRx coupon, you may be able to pay a lower price for your Trelegy Ellipta prescription. For instance, at certain pharmacies, one 100 mcg / 62.5 mcg / 25 mcg inhaler may cost as low as $688.77 with a GoodRx coupon. 

Here’s how to get the deal:

  • Visit the GoodRx website or install the GoodRx app on your mobile device.

  • Type “Trelegy Ellipta” in the search field.

  • Select the correct dose and quantity, and set your location.

  • Click or tap on “Search prices” to find prices at pharmacies near you.

  • Have your discount information sent to you via text or email, or print it. If you’re using the app, keep the discount ready on your phone’s screen, or save it to your digital wallet.

Show the coupon at the pharmacy when you pick up your medication. Or present the coupon to your pharmacy staff early on in the filling process, such as when you first receive your prescription, to help prevent delays at the pick-up counter.

2. See if you qualify for a copay savings card

If you have commercial insurance, you may be able to use a manufacturer copay savings card to help lower your cost. With a copay card, you may be able to pay as little as $0 for each covered 30-, 60-, or 90-day supply (1, 2, or 3 inhalers). This card is valid for up to 12 uses. Each individual inhaler counts as one use.

To be eligible for the Trelegy copay savings card, you need to:

  • Be a resident of the U.S. or a U.S. territory

  • Have a valid prescription for Trelegy Ellipta

  • Have commercial insurance

  • Not receive reimbursement for your Trelegy prescription from government-funded insurance, such as Medicare, Medicaid, or Tricare

You can sign up for the Trelegy copay savings card online. Your prescriber or pharmacist can also help you sign up.

3. See if you're eligible for a patient assistance program

GSK, the manufacturer of Trelegy Ellipta, also offers a patient assistance program for people without insurance. If you’re eligible, you may be able to receive Trelegy Ellipta at no cost. 

You may be eligible for Trelegy’s patient assistance program if you:

  • Are uninsured or have Medicare

  • Live in the U.S. or Puerto Rico

  • Have been prescribed Trelegy Ellipta by a U.S.-licensed prescriber for an FDA-approved use

  • Meet certain income requirements and can submit proof of income

You can apply by fax, mail, or phone. Your prescriber or pharmacist can also help you apply. For questions about eligibility or benefits, call 1-866-728-4368.

4. Request a larger supply

Ask your prescriber for a prescription for multiple inhalers. Filling multiple inhalers at once may reduce the cost for each individual inhaler. This is similar to other types of bulk discounts.

If you have insurance that covers Trelegy Ellipta, you can also ask about potential discounts for using your plan’s mail-order pharmacy.

5. Ask your prescriber about alternatives

If Trelegy Ellipta isn’t working well or you’re concerned about its cost, talk to your prescriber. There may be another medication that adequately treats your condition and fits your budget.

Many asthma medications and COPD medications are available to treat more severe symptoms beyond inhalers alone.

6. Use funds from a tax-advantaged account

If you have a health savings account (HSA), a flexible spending account (FSA) or a health reimbursement arrangement (HRA), using those funds to buy your medication can reduce your out-of-pocket costs through tax savings.

Frequently asked questions

If you have insurance, what you’ll pay for Trelegy depends on your specific plan. Many insurance plans, including Medicare, cover it. But your out-of-pocket cost will vary based on a few factors, such as your deductible, copay or coinsurance, and your plan’s formulary tier. Some people pay a lower copay, while others may pay more depending on their coverage.

Trelegy Ellipta is a brand-name inhaler that combines three medications into one device. Because there’s no generic alternative available yet, there’s no competition to drive the price down. Its cost also reflects the money it takes to conduct the research, clinical trials, and approval process required to bring the medication to market.

The bottom line

Trelegy Ellipta (fluticasone furoate / umeclidinium / vilanterol) is a maintenance inhaler that is used for the long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma. It contains three active ingredients that, together, help lessen inflammation and relax the air passages in the lungs.

Even without insurance, there are ways to save on Treley Ellipta. For example, the cost of one 100 mcg / 62.5 mcg / 25 mcg inhaler may be as low as $688.77 with a GoodRx coupon at certain pharmacies. And GSK, the maker of Trelegy Ellipta, offers multiple programs to help consumers reduce their out-of-pocket costs.

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Tamara E. Holmes
Written by:
Tamara E. Holmes
Tamara E. Holmes is a Washington, DC-based freelance journalist and content strategist who has been writing about personal finance, health, and health insurance for more than a decade. Her work has appeared in various print and online publications, such as USA Today, AARP, Working Mother, and Diversity Woman.
Cindy George, MPH, is the senior personal finance editor at GoodRx. She is an endlessly curious health journalist and digital storyteller.
Joshua Murdock, PharmD, BCBBS, is a licensed pharmacist in Arizona, Colorado, and Rhode Island. He has worked in the pharmacy industry for more than 10 years and currently serves as a pharmacy editor for GoodRx.

References

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