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Specialty Drug
NILOTINIB is a medicine that targets proteins in cancer cells and stops the cells from growing. It is used to treat chronic myelogenous leukemia (CML). Compare kinase inhibitors.
Prescription Settings
dose pack
28 capsules of 150mg
1 dose pack
dose pack
28 capsules of 150mg
1 dose pack

Tasigna Side Effects

What should I watch for?

Visit your doctor for checks on your progress. You will need to have regular blood tests while on this medicine. Report any new symptoms promptly. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Do not become pregnant while taking this medicine or for at least 14 days after. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for at least 14 days after the last dose.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

bleeding gums

blood in the urine or stools

blurred vision

bone pain


clay-colored stools



dark urine

decreased appetite

difficult or labored breathing

dry mouth



flushed, dry skin

fruit-like breath odor



increased hunger

increased thirst

increased urination

irregular heartbeat, recurrent

itching, skin rash

loss of appetite

lower back or side pain

muscle aches, cramps, or pain


no blood pressure

no breathing

no pulse

numbness, tingling, pain, or weakness in the hands or feet

painful or difficult urination

pale skin

pinpoint red spots on the skin


sore throat

stomach pain or tenderness

stuffy or runny nose


swelling of the hands, ankles, feet, or lower legs

tightness in the chest


troubled breathing with exertion

ulcers, sores, or white spots in the mouth

unexplained weight loss

unusual bleeding or bruising

unusual tiredness or weakness

weakness and heaviness of the legs

yellow eyes or skin

Less common

Decreased urine output


fast heartbeat

loss of consciousness

muscle cramps in the hands, arms, feet, legs, or face


numbness and tingling around the mouth, fingertips, or lips

rapid weight gain


Less common or rare

Bladder pain

bloody or cloudy urine

body aches or pain


cough producing mucus

depressed mood

dry skin and hair

ear congestion

feeling cold

frequent urge to urinate

hair loss

loss of voice

muscle stiffness

pain or tenderness around the eyes and cheekbones

sensitivity to heat

slowed heartbeat


swelling or puffiness of the face

tender, swollen glands in the neck

trouble sleeping

trouble swallowing

weight changes

white patches in the mouth or throat or on the tongue

Incidence not known

Pain or swelling of the treated skin

rapid, shallow breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

burning, itching, and pain in hairy areas


difficulty with moving

joint pain or swelling

lack or loss of strength

muscle spasms

pain in the arms or legs

pus at the root of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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