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Bosulif

Bosulif Side Effects

Jenny Zhang, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Jenny Zhang, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on January 11, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • High creatinine levels in blood (93%)
  • Diarrhea (80%)
  • Low blood cell counts (up to 72%)
  • High liver enzyme levels in blood (up to 58%%)
  • Nausea (44%)
  • Rash (44%)
  • Stomach pain (43%)
  • Vomiting (33%)
  • Fatigue (33%)
  • Respiratory tract infection (25%)
  • Fever (24%)
  • Headache (21%)

Less Common Side Effects

  • Constipation
  • Lower appetite
  • Joint pain
  • Back pain
  • Cough
  • Shortness of breath
  • Fluid buildup or swelling
  • Dizziness
  • Itching

Note: Side effects were reported by adults. Side effects for children might differ.

Bosulif serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Infections: repeated fevers, chills, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
  • Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, throwing up blood, blood in the urine, bloody or black and tarry stool
  • Liver damage: dark urine, right-sided stomach pain, yellowing of the eyes or skin, tiredness, loss of appetite, nausea, vomiting
  • Heart problems: chest pain, racing heartbeat, shortness of breath that usually worsens with activity or while lying flat, swelling of your legs or feet, sudden weight gain, fatigue, dizziness

Source: DailyMed

The following Bosulif side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

bleeding gums

blood in the urine or stools

chills

cough

difficult or labored breathing

fever

lower back or side pain

painful or difficult urination

pale skin

pinpoint red spots on the skin

sore throat

swelling of the hands, ankles, feet, or lower legs

tightness in the chest

troubled breathing with exertion

ulcers, sores, or white spots in the mouth

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Agitation

chest pain or discomfort

clay-colored stools

cough with mucus

confusion

dark urine

decreased appetite

decreased urination

depression

diarrhea

dizziness

dry mouth

fainting

fast or irregular heartbeat

general feeling of discomfort or illness

headache

hives, itching, or skin rash

hoarseness

hostility

increased sweating

increased thirst

irritation

joint pain, stiffness or swelling

lightheadedness

loss of appetite

muscle aches, pains, or twitching

nausea

numbness or tingling in the hands, feet, or lips

rapid breathing

rapid weight gain

redness of the skin

runny nose

seizures

shivering

sneezing

stomach pain or tenderness

sunken eyes

swelling of the eyelids, face, lips, hands, or feet

thirst

trouble sleeping

trouble swallowing

vomiting

weakness or heaviness of the legs

wrinkled skin

Rare

Blistering, peeling, or loosening of the skin

bloating

blue lips, fingernails, or skin

chest pain, possibly moving to the left arm, neck, or shoulder

constipation

coughing that sometimes produces a pink frothy sputum

difficult, noisy breathing

indigestion

irregular, fast or slow, or shallow breathing

pains in the stomach, side, or abdomen, possibly radiating to the back

puffiness or swelling of the eyelids or around the eyes, face, lips or tongue

red, irritated eyes

vomiting of blood or material that looks like coffee grounds

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

difficulty with moving

lack or loss of strength

muscle stiffness

stuffy nose

Less common

Blemishes on the skin

burning feeling in the chest or stomach

change in taste

hearing loss

loss of taste

muscle cramping

pimples

ringing, buzzing, or other unexplained noise in the ears that continues

stomach upset

Rare

Flaking and falling off of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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