The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- High creatinine levels in blood (93%)
- Diarrhea (80%)
- Low blood cell counts (up to 72%)
- High liver enzyme levels in blood (up to 58%%)
- Nausea (44%)
- Rash (44%)
- Stomach pain (43%)
- Vomiting (33%)
- Fatigue (33%)
- Respiratory tract infection (25%)
- Fever (24%)
- Headache (21%)
Less Common Side Effects
- Constipation
- Lower appetite
- Joint pain
- Back pain
- Cough
- Shortness of breath
- Fluid buildup or swelling
- Dizziness
- Itching
Note: Side effects were reported by adults. Side effects for children might differ.
Bosulif serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Infections: repeated fevers, chills, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
- Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, throwing up blood, blood in the urine, bloody or black and tarry stool
- Liver damage: dark urine, right-sided stomach pain, yellowing of the eyes or skin, tiredness, loss of appetite, nausea, vomiting
- Heart problems: chest pain, racing heartbeat, shortness of breath that usually worsens with activity or while lying flat, swelling of your legs or feet, sudden weight gain, fatigue, dizziness
Source: DailyMed
The following Bosulif side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Black, tarry stools
bleeding gums
blood in the urine or stools
chills
difficult or labored breathing
lower back or side pain
painful or difficult urination
pale skin
pinpoint red spots on the skin
swelling of the hands, ankles, feet, or lower legs
tightness in the chest
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
Less common
Agitation
chest pain or discomfort
clay-colored stools
cough with mucus
confusion
dark urine
decreased appetite
decreased urination
dizziness
fainting
fast or irregular heartbeat
general feeling of discomfort or illness
headache
hoarseness
hostility
increased sweating
increased thirst
irritation
joint pain, stiffness or swelling
lightheadedness
loss of appetite
muscle aches, pains, or twitching
numbness or tingling in the hands, feet, or lips
rapid breathing
rapid weight gain
redness of the skin
seizures
shivering
stomach pain or tenderness
sunken eyes
swelling of the eyelids, face, lips, hands, or feet
thirst
trouble sleeping
trouble swallowing
vomiting
weakness or heaviness of the legs
wrinkled skin
Rare
Blistering, peeling, or loosening of the skin
blue lips, fingernails, or skin
chest pain, possibly moving to the left arm, neck, or shoulder
coughing that sometimes produces a pink frothy sputum
difficult, noisy breathing
indigestion
irregular, fast or slow, or shallow breathing
pains in the stomach, side, or abdomen, possibly radiating to the back
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
red, irritated eyes
vomiting of blood or material that looks like coffee grounds
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Blemishes on the skin
burning feeling in the chest or stomach
change in taste
hearing loss
loss of taste
muscle cramping
ringing, buzzing, or other unexplained noise in the ears that continues
stomach upset
Rare
Flaking and falling off of the skin
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

