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Iclusig

Iclusig Side Effects

Lauren Morton, PharmD, BCPSCydnee Ng, PharmD
Reviewed by Lauren Morton, PharmD, BCPS, Cydnee Ng, PharmD
Last reviewed on August 24, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Rash (up to 75%)
  • Joint pain (up to 61%)
  • Stomach pain (up to 54%)
  • Constipation (up to 53%)
  • High blood pressure (up to 53%)
  • Tiredness (up to 47%)
  • Headache (up to 43%)
  • Dry skin (up to 42%)
  • Swelling or fluid buildup (up to 41%)
  • Fever (up to 40%)
  • Nausea (up to 34%)
  • Lower appetite (up to 31%)

Less Common Side Effects

Iclusig serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Blood clots or reduced blood flow problems: chest pain, trouble breathing, weakness on one side of the body, trouble talking, changes in vision, severe headache, leg pain or swelling
  • Severe fluid buildup or heart failure: shortness of breath during rest or exercise, rapid weight gain, swelling in your arms or legs, chest pain, tiredness
  • Changes in your heart rhythm: fainting, dizziness, chest pain, fast heartbeat
  • Liver damage: right-sided stomach pain, tiredness, loss of appetite, yellowing of the skin or eyes
  • Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
  • Abnormal electrolyte levels and kidney problems: racing heart, muscle cramps or spasms, numbness, dark urine, urinating less than usual
  • Problems that affect the brain: headaches, vision problems, seizures

Source: DailyMed

The following Iclusig side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bladder pain

bleeding gums

bloating or swelling of the face, arms, hands, lower legs, or feet

blurred vision

chest pain

chills

cloudy urine

confusion

constipation

cough or hoarseness

coughing up blood

decreased urine output

difficult, burning, or painful urination

difficulty with breathing or swallowing

dilated neck veins

dizziness

fainting

frequent urge to urinate

increased menstrual flow or vaginal bleeding

indigestion

irregular breathing

joint pain, stiffness, or swelling

lightheadedness

lower back, side, or stomach pain

nervousness

nosebleeds

pains in the chest, groin, or legs, especially calves of the legs

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

paralysis

pinpoint red spots on the skin

pounding in the ears

prolonged bleeding from cuts

rapid weight gain

rapid, shallow breathing

red or black, tarry stools

red or dark brown urine

severe headaches of sudden onset

slow or fast heartbeat

sore throat

sudden loss of coordination

sudden slurred speech

sudden vision changes

tingling of the hands or feet

ulcers, sores, or white spots in the mouth

unusual bleeding or bruising

unusual weight gain or loss

Less common

Anxiety

burning, numbness, tingling, or painful sensations

chest discomfort

fast, pounding, or irregular heartbeat or pulse

pain, redness, or swelling in the arms or legs

unsteadiness or awkwardness

weakness in the arms, hands, legs, or feet

Incidence not known

Blistering, peeling, loosening of the skin

bloody, black, or tarry stools

blue-green halos seen around objects

clay-colored stools

dark urine

decreased appetite

diarrhea

dry eyes

fever

headache

heartburn

indigestion

itching or skin rash

joint or muscle pain

loss of appetite

nausea and vomiting

red irritated eyes

red skin lesions, often with a purple center

sensitivity of the eyes to light

sensitivity to heat

severe vomiting, sometimes with blood

sore throat

stomach cramps or tenderness

sweating

trouble sleeping

unusual tiredness or weakness

vomiting of material that looks like coffee grounds, severe and continuous

weight loss

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back or bone pain

cracked lips

difficulty having a bowel movement (stool)

difficulty with moving

dryness, itching, pain, redness, swelling, tenderness, or warmth on the skin

lack or loss of strength

muscle aches, pain, or stiffness

stuffy or runny nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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