Therapeutic ClassificationsAntibiotic
QUICK LINKS
- Overview
- Proper Use
- Dosing
- Missed Dose
- Use & Storage
- Before Using
- Allergies
- Pediatric
- Geriatric
- Pregnancy
- Breast Feeding
- Drug Interactions
- Other Interactions
- Other Medical Problems
- Precautions
- Chemical Classifications
OverviewTOP
Sulfadiazine is used to treat or prevent infections in many different parts of the body. It belongs to the group of medicines known as sulfonamide antibiotics. It works by preventing the growth of bacteria. However, this medicine will not work for colds, flu, or other virus infections.
This medicine is available only with your doctor's prescription.
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Proper UseTOP
This medicine should not be given to infants younger than 2 months of age unless directed by your child's doctor. Sulfadiazine may cause serious unwanted effects in this age group.
Take this medicine with a full glass (8 ounces) of water. Several additional glasses of water should be taken during the day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects.
This medicine works best when there is a constant amount in the blood or urine. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help in planning the best times to take your medicine, check with your doctor.
To help clear up your infection completely, keep using this medicine for the full treatment time, even if you feel better after the first few doses. If you stop taking this medicine too soon, your symptoms may return.
DosingTOP
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- For treatment of infections:
- Adults—2000 to 4000 milligrams (mg) per day, divided and given in 3 to 6 doses per day.
- Children and infants 2 months of age and older—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 75 milligrams (mg) per kilogram (kg) of body weight per day (mg/kg/day), divided and given in 4 to 6 doses per day. Your doctor may increase your dose to 150 mg/kg/day, but the total dose is usually not more than 6000 mg per day.
- Infants younger than 2 months of age—Use is not recommended.
- For prevention of rheumatic fever:
- Adults and children 30 kilograms (kg) or more—1000 milligrams (mg) per day as a single dose.
- Adults and children less than 30 kilograms (kg)—500 milligrams (mg) per day as a single dose.
- For treatment of infections:
Missed DoseTOP
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Use & StorageTOP
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Before UsingTOP
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
AllergiesTOP
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
PediatricTOP
Because of sulfadiazine's toxicity, use in infants younger than 2 months of age is not recommended.
GeriatricTOP
No information is available on the relationship of age to the effects of sulfadiazine in geriatric patients. However, elderly patients are more likely to have age-related kidney and liver problems, which may require caution in patients receiving sulfadiazine.
PregnancyTOP
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breast FeedingTOP
Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.
Drug InteractionsTOP
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Methenamine
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acetohexamide
- Aminolevulinic Acid
- Cyclosporine
Other InteractionsTOP
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical ProblemsTOP
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Asthma or
- Blood problems (e.g., agranulocytosis, aplastic anemia) or
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency (an enzyme problem) or
- Kidney disease or
- Liver disease—Use with caution. May have an increased chance of side effects.
PrecautionsTOP
If your symptoms do not improve within a few days or if they become worse, check with your doctor.
Check with your doctor right away if you have fever, chills, pale skin, pinpoint red or purple spots on the skin, sore throat, pain in the upper stomach, or yellow eyes or skin. These may be symptoms of a serious blood problem.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
