The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Injection-site reactions (pain, itching, redness, bruising, swelling; 14-19%)
- Headache (9%)
- Constipation (8-9%)
- Nausea (8-9%)
- Vomiting (6-9%)
Less Common Side Effects
- Fatigue
- Sleepiness
- Dizziness
Sublocade serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Dangerously slow breathing: trouble breathing; bluish-colored lips, fingers, or toes
- Opioid withdrawal: suicidal thoughts, anxiety, restlessness, runny nose, yawning, sweating, chills, wide pupils, irritability
- Heart rhythm problems: chest pounding, fluttering in the chest, difficulty breathing, chest pain, feeling faint or lightheaded
- Serious injection site reaction: skin sore or ulcer
- Serious allergic reactions: rash, hives, itchiness, shortness of breath, low blood pressure, fast heartbeat, dizziness, fatigue, flushing (feeling warm all of a sudden)
Source: DailyMed
The following Sublocade side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake
- Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
- Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
- Pain or trouble swallowing, heartburn, chest pain
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Constipation
- Dizziness
- Drowsiness
- Dry mouth
- Headache
- Nausea
- Pain, redness, or irritation at injection site
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