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Talwin NX

Talwin NX Side Effects

Ashley Wong, PharmDCydnee Ng, PharmD
Reviewed by Ashley Wong, PharmD, Cydnee Ng, PharmD
Last reviewed on December 16, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Sleepiness or tiredness
  • Dizziness
  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Headache
  • Sweating
  • Itchiness

Less Common Side Effects

  • Changes in blood pressure
  • Lightheadedness or feeling faint when standing from a sitting or lying down position
  • Fast heartbeat
  • Fainting
  • Hallucinations
  • Disturbing dreams
  • Trouble sleeping (insomnia)
  • Depression
  • Confusion
  • Seizures
  • Flushing
  • Loss of appetite
  • Dry mouth
  • Vision changes
  • Trouble urinating

Talwin NX serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reactions: trouble breathing, swelling of your face, tongue, or throat
  • Severe drowsiness or slowed breathing
  • Overdose: slowed breathing, severe drowsiness or sleepiness, not feeling as aware, not responding to sound or touch, slow heartbeat, small pupils the size of a pinhead, blue-gray skin tone
  • Withdrawal: uncontrolled pain, suicidal thoughts, sweating, restlessness, nausea, vomiting, diarrhea, muscle pain, watery eyes, wide pupils
  • Serotonin syndrome: high fever, hallucinations, racing heart, unstable blood pressure, sudden changes in thought, mood, and movement, feeling uneasy or nervous, stiff muscles
  • Chest pain
  • Trouble walking

Source: DailyMed

The following Talwin NX side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Black, tarry stools

chest pain

chills

cough

difficult or troubled breathing

fever

general feeling of tiredness or weakness

hoarseness

irregular, fast or slow, or shallow breathing

lower back or side pain

painful or difficult urination

pale or blue lips, fingernails, or skin

shakiness in the legs, arms, hands, or feet

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

trembling or shaking of the hands or feet

unusual bleeding or bruising

unusual tiredness or weakness

Incidence not known

Agitation

blistering, peeling, or loosening of the skin

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

confusion

constipation

constricted, pinpoint, or small pupils (black part of the eye)

darkening of the skin

decrease in the frequency of urination

depression

diarrhea

difficulty in passing urine (dribbling)

difficulty with swallowing

dizziness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

excitement

fainting

false or unusual sense of well-being

fast, slow, pounding, or irregular heartbeat or pulse

feeling of warmth

headache

hives or welts, itching, skin rash

joint or muscle pain

loss of bladder control

loss of consciousness

nervousness

overactive reflexes

poor coordination

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid breathing

red skin lesions, often with a purple center

red, irritated eyes

redness of the face, neck, arms, and occasionally, upper chest

restlessness

sweating

swelling of the face, arms, or lower legs

tightness in the chest

total body jerking

upper abdominal or stomach pain

weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Chest pain

choking

cold and clammy skin

constricted, pinpoint, or small pupils (black part of the eye)

coughing that sometimes produces a pink frothy sputum

decreased awareness or responsiveness

difficult, fast, or noisy breathing

extremely shallow or slow breathing

increased sweating

loss of consciousness

no muscle tone or movement

pale skin

seeing, hearing, or feeling things that are not there

severe sleepiness or unusual drowsiness

seizures (convulsions)

slow heartbeat

swelling in the legs and ankles

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

Stomach distress

Incidence not known

Continuing ringing or buzzing or other unexplained noise in the ears

cracked, dry, or scaly skin

difficulty in focusing the eyes

disturbed dreams

drowsiness

dry mouth

hearing loss

irritability

lightheadedness

loss of appetite

mood or mental changes

nausea

relaxed and calm feeling

trouble with sleeping

vomiting

weakness

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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