The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Injection and nasal spray:
- Drowsiness (49%)
- Dizziness (23%)
- Nausea or vomiting (8%)
Nasal spray only:
- Stuffy nose (13%)
- Trouble sleeping (11%)
Less Common Side Effects
- Headache
- Weakness
- Constipation
- Dry mouth
- Tremor or shakiness
- Confusion
- Anxiety
- Sweating
- Itching
Butorphanol serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: hives, trouble breathing, swelling in your lips, tongue, throat, or face
- Slowed breathing
- Accidentally taking too much (overdose): slowed breathing, extreme sleepiness, stiff muscles, feeling cold and sweaty
- Opioid withdrawal: restlessness, muscle or joint pain, runny nose, yawning or sweating more than usual, chills, irritability, anxiety
- Seizures
- Dangerously low blood pressure: dizziness, fainting
Source: DailyMed
The following Butorphanol side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Bloody nose
body aches or pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chills
cough producing mucus
difficult or labored breathing
ear congestion
fast, irregular, pounding, or racing heartbeat or pulse
feeling faint, dizzy, or lightheaded
feeling of warmth or heat
flushing or redness of the skin, especially on the face and neck
headache
loss of voice
shakiness in the legs, arms, hands, or feet
sweating
tightness in the chest
trembling or shaking of the hands or feet
unusual tiredness or weakness
Rare
Blurred vision
confusion
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fainting
shallow breathing
Incidence not known
Agitation
bluish lips or skin
confusion
darkening of the skin
difficulty swallowing
loss of appetite
mental depression
not breathing
overactive reflexes
poor coordination
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
restlessness
seizures
shivering
sweating
talking or acting with excitement you cannot control
tightness in the chest
twitching
vomiting
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Change in consciousness
choking
cold and clammy skin
constricted, pinpoint, or small pupils (black part of the eye)
coughing that sometimes produces a pink frothy sputum
decreased awareness or responsiveness
difficult, fast, or noisy breathing
extremely shallow or slow breathing
increased sweating
loss of consciousness
no muscle tone or movement
pale skin
severe sleepiness
slow heartbeat
swelling in the legs and ankles
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Sleepiness or unusual drowsiness
trouble sleeping
Less common
Bad or unusual or unpleasant (after) taste
continuing ringing or buzzing or other unexplained noise in the ears
difficulty having a bowel movement
ear pain
false or unusual sense of well-being
fear or nervousness
floating feeling
hearing loss
lack or loss of strength
pain or tenderness around the eyes and cheekbones
stomach pain
tender, swollen glands in the neck
trouble with swallowing
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
voice changes
Incidence not known
False beliefs that cannot be changed by facts
feeling of constant movement of self or surroundings
sensation of spinning
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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