Typical dosage for Soliris
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Adults
- PNH: The typical dose is 600 mg as an infusion through the vein (IV) every week for the first 4 weeks, 900 mg on week 5, then 900 mg every 2 weeks thereafter.
- aHUS, gMG, or NMOSD: The typical dose is 900 mg IV every week for the first 4 weeks, 1,200 mg on week 5, then 1,200 mg every 2 weeks thereafter.
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Children younger than 18 years old with aHUS or children 6 to 18 years old with gMG
- Weigh 88 lbs or more: The typical dose is 900 mg IV every week for the first 4 weeks, 1,200 mg on week 5, then 1,200 mg every 2 weeks thereafter.
- Weigh 66 lbs to less than 88 lbs: The typical dose is 600 mg IV every week for the first 2 weeks, 900 mg on week 3, then 900 mg every 2 weeks thereafter.
- Weigh 44 lbs to less than 66 lbs: The typical dose is 600 mg IV every week for the first 3 weeks, then 600 mg every 2 weeks thereafter.
- Weigh 22 lbs to less than 44 lbs: The typical dose is 600 mg IV on week 1, 300 mg on week 2, then 300 mg every 2 weeks thereafter.
- Weigh 11 lbs to less than 22 lbs: The typical dose is 300 mg IV for the first 2 weeks, then 300 mg every 3 weeks thereafter.
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