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Soliris
Specialty Drug

Eculizumab

ECULIZUMAB is a monoclonal antibody. It is used to treat a rare kind of anemia called paroxysmal nocturnal hemoglobinuria or PNH. It may help prevent the loss of blood in patients with PNH. Compare complement inhibitors.
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Soliris Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine. You will need regular blood work. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may have sudden breakdown of your red blood cells after you stop taking this medicine. You will need to be followed by your doctor for 8 weeks or more after this therapy is complete.

This medicine may decrease your body's ability to fight infection. Avoid being around people who are sick.

Carry the Patient Safety Card given to you at all times. Seek medical help if you have any of the symptoms listed on the card.

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Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Back pain

black, tarry stools

bladder pain

bloody or cloudy urine

blurred vision

burning or stinging of the skin

chest pain

cough

difficult, burning, or painful urination

difficulty with moving

dizziness

fever

headache

joint pain

lower back or side pain

muscle aching or cramping

muscle pains or stiffness

nausea

nervousness

pain or tenderness around the eyes and cheekbones

painful cold sores or blisters on the lips, nose, eyes, or genitals

pale skin

pounding in the ears

shortness of breath or troubled breathing

slow or fast heartbeat

sneezing

sore throat

sores, ulcers, or white spots on lips or in the mouth

stuffy or runny nose

swollen glands

swollen joints

tightness of the chest or wheezing

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Chills

diarrhea

general feeling of discomfort or illness

loss of appetite

shivering

sweating

trouble sleeping

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty having a bowel movement (stool)

pain in the arms or legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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