The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Changes in liver enzymes (70-75%)
- Nausea (45-47%)
- Muscle pain (35-45%)
- Tiredness (22-36%)
- Headache (22-36%)
- Infection (27-36%)
- Febrile neutropenia (27-30%)
- Fever (20-30%)
- Bleeding (24-27%)
- Mouth sores (24-27%)
- Stomach pain (24-27%)
- Lower appetite (21-27%)
- Diarrhea (18-25%)
- Allergic reaction (21-24%)
- Pancreatitis (12-22%)
- Low potassium in blood (9-22%)
- High blood sugar (12-21%)
Less Common Side Effects
- High heart rate
- Cough
- Dehydration
- Nerve damage
- Trouble sleeping
Rylaze serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: trouble breathing, hives, itching, facial swelling, dizziness, fainting
- Pancreatitis: severe stomach pain, fever, nausea, vomiting, chills, diarrhea
- Blood clots: sudden and severe headache, swelling in the arms or legs, trouble breathing, chest pain
- Bleeding: unusual bruising, nose bleeds
- Severe liver problems: sudden weight gain, stomach pain or swelling, nausea, vomiting, yellowing of the skin or the whites of the eyes
Source: DailyMed
The following Rylaze side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Fatigue
- Headache
- Loss of appetite
- Muscle pain
- Nausea
- Pain, redness, or swelling with sores inside the mouth or throat
- Stomach pain
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