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Oncaspar

Oncaspar Side Effects

Allison Baxley, PharmD, BCOPDaisy Chau, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Daisy Chau, PharmD
Last reviewed on September 3, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • High liver enzymes (66%)
  • Neutropenic fever (40%)
  • High triglycerides (30%)
  • Low albumin (28%)
  • High bilirubin (25%)
  • High blood sugar (24%)
  • Pancreatitis (24%)
  • Abnormal clotting labs (up to 21%)

Note: Only serious side effects are shown above from a study where [[EDITOR|DRUG_DISPLAY_NAME]] was given with other medications, so these side effects might not be solely due to [[EDITOR|DRUG_DISPLAY_NAME]].

Less Common Side Effects

  • Allergic reactions
  • Blood clots
  • Pneumonia
  • Sepsis
  • Diarrhea
  • Bleeding
  • Fungal infection

Oncaspar serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: facial swelling, rash, redness, itching, trouble breathing
  • Severe liver problems: sudden weight gain, stomach pain or swelling, nausea, vomiting, yellowing of the skin or the whites of the eyes
  • Pancreatitis: fever, nausea, vomiting, severe stomach pain, chills, diarrhea
  • Blood clots: sudden and severe headache, swelling in the arms or legs, trouble breathing, chest pain

Source: DailyMed

The following Oncaspar side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

bloating

blurry vision

chills

constipation

cough

dark urine

difficulty breathing

dry mouth

fast heartbeat

fever

flushed, dry skin

fruit-like breath odor

hives, itching, skin rash

hoarseness

increased hunger

increased thirst

increased urination

indigestion

irritation

joint pain, stiffness, or swelling

loss of appetite

nausea

pain in the chest, groin, or legs, especially the calves

painful or difficult urination

pains in the stomach, side, or abdomen, possibly radiating to the back

redness of the skin

severe, sudden headache

skin paleness

slurred speech

sore throat

stomach pain

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

sweating

swelling of the eyelids, face, lips, hands, or feet

tightness in the chest

troubled breathing

troubled swallowing

ulcers, sores, or white spots in the mouth

unexplained weight loss

unusual bleeding or bruising

unusual tiredness or weakness

vision changes

vomiting

yellow eyes or skin

Incidence not known

Continuing nausea or vomiting

increase in the frequency of seizures

light-colored stools

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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