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Ribavirin

Ribavirin Side Effects

Hope Chang, PharmD, AAHIVPThienLy Neal, PharmD
Reviewed by Hope Chang, PharmD, AAHIVP, ThienLy Neal, PharmD
Last reviewed on July 7, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

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  • Headache
  • Fever
  • Muscle aches
  • Tiredness or weakness
  • Shaking chills
  • Nausea
  • Changes in mood, feeling more irritable
  • Vomiting
  • Not feeling as hungry

Less Common Side Effects

  • Sweating
  • Hard time concentrating
  • Stomach pain
  • Infections
  • Change in taste
  • Difficulty falling asleep
  • Constipation
  • Blurred vision

Ribavirin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions (hives, difficulty breathing, swelling of face, mouth, lips, or throat)
  • Severe stomach pain that spreads to your back along with nausea and vomiting (signs of pancreatitis)
  • Serious eye problems that can lead to loss of vision
  • Serious blood disorders that can lead to heart attacks
  • Serious lung infections
  • Worsening of depression or thoughts of harm to self or others

Source: DailyMed

The following Ribavirin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Anxiety

black, tarry stools

body aches or pain

chest pain

congestion

cough or hoarseness

crying

depersonalization

diarrhea

difficult or labored breathing

discouragement

dry mouth

dryness of the throat

dysphoria

euphoria

feeling sad or empty

feeling unusually cold

fever or chills

general feeling of discomfort or illness

headache

hyperventilation

irregular heartbeats

irritability

joint pain

lack of appetite

loss of interest or pleasure

lower back or side pain

mental depression

muscle aches and pains

nausea

nervousness

painful or difficult urination

pale skin

paranoia

poor concentration

quick to react or overreact emotionally

rapidly changing moods

restlessness

right upper abdominal or stomach pain

runny nose

shaking

shivering

shortness of breath

sleeplessness

sore throat

sores, ulcers, or white spots on the lips or in the mouth

sweating

tender, swollen glands in the neck

tightness in the chest

trouble with concentrating

trouble with sleeping

trouble with swallowing

troubled breathing with exertion

unable to sleep

unusual bleeding or bruising

unusual tiredness or weakness

voice changes

vomiting

wheezing

Less common

Bleeding gums

blood in the urine or stools

constipation

depressed mood

dry skin and hair

feeling cold

hair loss

husky voice

muscle cramps and stiffness

pinpoint red spots on the skin

right upper abdominal or stomach fullness

slowed heartbeat

weight gain

Incidence not known

Blistering, flaking, or peeling of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

being forgetful

belching

blurred vision

bone pain

change in taste or bad, unusual, or unpleasant (after) taste

cracked, scaly skin

crusting, irritation, itching, or reddening of the skin

difficulty with moving

dizziness or lightheadedness

feeling of constant movement of self or surroundings

hair loss or thinning of the hair

heartburn

indigestion

lack or loss of strength

menstrual changes

pain or tenderness around the eyes and cheekbones

rash

sensation of spinning

sneezing

stomach discomfort, upset, or pain

stuffy nose

swelling

swollen joints

weight loss

Less common

Back pain

burning, dry, or itching eyes

discharge, excessive tearing

feeling of warmth

redness of the face, neck, arms, and occasionally, upper chest

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

skin rash, encrusted, scaly, and oozing

Incidence not known

Change in hearing

loss of hearing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Hope Chang is a freelance writer and content reviewer for GoodRx. She attended Howard University College of Pharmacy in Washington, D.C. and completed post-graduate residency training at the University of California, Davis Medical Center.
ThienLy Neal, PharmD, has over 10 years experience in the pharmacy field, including in such settings as retail, hospital, compounding, and managed care. She has led various clinical programs while focusing on medication adherence programs, specialty drug initiatives, and polypharmacy safety initiatives.

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