The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Injection site reactions (swelling, redness, pain, tenderness, mild pain)
Less Common Side Effects
- Mild fever
- Skin rash
- Body aches
Rhogam serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reactions: wheezing, chest tightness, trouble breathing, low blood pressure, dizziness, vomiting, itchy rash, hives, tongue or throat swelling
- Breakdown of red blood cells: fever, back pain, nausea, vomiting, shaking, chills, changes in blood pressure, discolored urine, or blood in urine
Source: DailyMed
The following Rhogam side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Hemolytic anemia—unusual weakness or fatigue, dizziness, headache, trouble breathing, dark urine, yellowing skin or eyes
- Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Chills
- Dizziness
- Headache
- Pain, redness, or irritation at injection site

