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Octagam

Octagam Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on August 30, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Octagam 5%:

  • Headache (15%)
  • Nausea (7%)

Octagam 10%:

  • Headache (25-42%)
  • Fever (15-19%)
  • Nausea (16% DM only)
  • Fast heart rate (11%, chronic ITP only)

Less Common Side Effects

  • Vomiting
  • Chills
  • Muscle or bone pain
  • Higher blood pressure
  • Confusion
  • Changes in vision
  • Difficulty breathing

Octagam serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Blood clots: lungs (cough, difficulty breathing, chest pain); legs (redness, pain, tenderness, swelling of the skin); heart attack (chest pain, pain in the arms or shoulders, pain in the neck or jaw); stroke (difficulty speaking, numbness on one side of the body, confusion)
  • Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
  • Serious allergic reaction: difficulty breathing, tightness in the throat, swelling in the face or tongue, hives, itching, fast heartbeat, nausea, stomach pain, dizziness, lightheadedness
  • Breakdown of red blood cells: tiredness, dizziness, weakness, yellowing of the skin or eyes, dark-colored urine
  • Brain inflammation: severe headache, neck stiffness, sensitivity to light, painful eye movements
  • Lung problems: severe breathing problems, chest pain or tightness

Source: DailyMed

The following Octagam side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
  • Fever, neck pain or stiffness, sensitivity to light, headache, nausea, vomiting, confusion, which may be signs of meningitis
  • Hemolytic anemia—unusual weakness or fatigue, dizziness, headache, trouble breathing, dark urine, yellowing skin or eyes
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Low sodium level—muscle weakness, fatigue, dizziness, headache, confusion
  • Shortness of breath or trouble breathing, cough, unusual weakness or fatigue, blue skin or lips

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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