The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Long-term ITP and severe/refractory aplastic anemia:
- Nausea (4-33%)
- Fever (9-14%)
- Tiredness (5-28%)
- Cough (9-23%)
- Headache (10-21%)
- Diarrhea (9-21%)
The risk of developing these side effects depends on your dose.
Long-term hepatitis C:
- Low red blood cell levels (anemia) (40%)
- Fever (30%)
- Tiredness (28%)
- Headache (21%)
- Nausea (19%)
- Diarrhea (19%)
People with hepatitis C who reported side effects were also taking interferon and ribavirin together with Promacta (eltrombopag). All of the listed side effects for people with long-term hepatitis C might not be caused by Promacta (eltrombopag) alone.
Less Common Side Effects
- Flu virus
- Muscle pain
- New or worsening cloudiness in the eye (cataracts)
- Back pain
- Tingling feeling
Promacta serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Liver damage: stomach swelling, dark stool or urine, tiredness, confusion, and yellowing of the skin or eyes
- Blood clot in the liver: nausea, vomiting, abdominal pain, and diarrhea
- Other types of blood clots: legs, (redness, pain, tenderness, swelling of the skin), lungs (cough, difficulty breathing, chest pain), heart attack (chest pain, pain in the arms or shoulders, pain in the neck or jaw), stroke (difficulty speaking, numbness on one side of the body, confusion)
Source: DailyMed
The following Promacta side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bloating or swelling of the face, arms, hands, lower legs, or feet
body aches or pain
chills
difficulty with breathing
headache
loss of voice
pain in the chest, groin, or legs, especially the calves
pale skin
rapid weight gain
severe, sudden headache
slurred speech
sudden loss of coordination
sudden, severe weakness or numbness in the arm or leg
tingling of the hands or feet
troubled breathing with exertion
unusual tiredness or weakness
unusual weight gain or loss
yellow eyes or skin
Less common
Bladder pain
blindness
blurred or decreased vision
bruising
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
general feeling of discomfort or illness
hoarseness
joint pain
lower back or side pain
muscle aches and pains
pinpoint red spots on the skin
redness of the eye
shivering
sweating
tender, swollen glands in the neck
trouble sleeping
trouble swallowing
voice changes
vomiting
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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