The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Adults:
- Joint stiffness (26%)
- Dizziness (17%)
- Trouble sleeping (16%)
- Muscle pain (14%)
- Arm or leg pain (13%)
- Stomach pain (11%)
Children:
- Bruising (41%)
- Cough, runny nose, and other symptoms of an upper respiratory tract infection (31%)
- Mouth and throat pain (25%)
- Fever (24%)
- Diarrhea (20%)
- Rash (15%)
- Stomach pain (14%)
Less Common Side Effects
Adults:
- Shoulder pain
- Heartburn
- Tingling sensation in the arms, legs, hands, or feet
Children:
- Purple spots on the skin (from damaged small blood vessels)
- Swelling in the arms and legs
- Hives
- Ear, stomach, and sinus infection, redness, or swelling
Nplate serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: rash, hives, itching, red, swollen, blistered, or peeling skin with or without fever, wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat
- Blood clot in the liver: upper stomach pain, nausea, vomiting, diarrhea
- Other types of blood clots: legs or arms (swelling, redness, pain), lungs (difficulty breathing, chest pain), heart attack (chest pain, pain in the arms or shoulders, pain in the neck or jaw, shortness of breath), stroke (numbness, tingling feeling, difficulty speaking, confusion)
Source: DailyMed
The following Nplate side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Bloating or swelling of the face, arms, hands, lower legs, or feet
body aches or pain
change in hearing
chills
difficulty breathing
ear congestion, drainage, or pain
headache
loss of appetite
loss of voice
pain or tenderness around the eyes and cheekbones
rapid weight gain
stomach pain
stuffy or runny nose
tightness of the chest
tingling of the hands or feet
unusual tiredness or weakness
unusual weight gain or loss
upper stomach pain
Incidence not known
Burning pain, warmth, swelling, or redness of the hands and feet
fast heartbeat
feeling of warmth
hoarseness
irritation
joint pain, stiffness, or swelling
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
redness of the skin
trouble swallowing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Acid or sour stomach
belching
bruise
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
difficulty with moving
dizziness
indigestion
mouth or throat pain
muscle pains, cramps, or stiffness
pain in the shoulder, arms, or legs
stomach discomfort, upset, or pain
trouble sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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