Prexxartan is part of the ARBs class and treats Heart Failure, Hypertension and Heart Attack. ARBs are used to lower blood pressure to treat hypertension, heart failure, diabetic nephropathy, coronary artery disease, heart attack, and for stroke risk reduction. They work by relaxing blood vessels allowing more efficient pumping of the heart and better blood flow. Prexxartan is only available as a brand name drug.