Pediarix
Pediarix is a combination vaccine that protects your child from infections due to diphtheria, tetanus, pertussis (collectively also known as DTaP), hepatitis B, and poliomyelitis (or polio). This vaccine is a 3-dose series, typically given to children ages 6 weeks to 6 years old as injections into the muscle.
What is Pediarix?
What is Pediarix used for?
Prevention of:
Diphtheria
Tetanus
Pertussis (whooping cough)
Hepatitis B
Poliovirus
How Pediarix works
Pediarix is an inactivated vaccine that protects your child from three types of bacteria (Corynebacterium diphtheriae (diphtheria), Clostridium tetani (tetanus), and Bordetella pertussis (pertussis), and two viruses (hepatitis B virus and poliovirus). The vaccine helps your child's immune system make antibodies that will attack these bacteria or viruses if they ever infect your child.
Drug Facts
Get your GoodRx coupon
What are the side effects of Pediarix?
Common Side Effects
- Pain at injection site
- Redness at injection site
- Swelling at injection site
- Fever
- Drowsiness
- Irritability
- Loss of appetite
Other Side Effects
- Diarrhea
- Vomiting
- Restlessness
- Trouble sleeping
- Rash
Serious Side Effects
- Serious allergic reaction: rash, nausea, dizziness, shortness of breath, chest pain, swelling of lips, tongue, throat, or face
Source: DailyMed
The following side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Feeling faint or lightheaded
- High fever
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
Pros and cons of Pediarix
Pros
More convenient since Pediarix is a combination vaccine
Can be given with other vaccines
Works well to prevent diphtheria, tetanus, whooping cough, hepatitis B, and polio
Cons
Can only be given as an injection into the muscle
Must be given by a healthcare provider at an office, clinic, or pharmacy
Not the best option for people allergic to latex (tip caps of the prefilled syringes are made with latex)
Pharmacist tips for Pediarix
Read the vaccine information statement for DTaP, hepatitis B, and polio for more information.
Let your child's provider know if your child has a history of seizures. Sometimes, a fever that results from a vaccine can trigger seizures. Your child's provider might recommend that your child take medication to lower fevers (e.g., acetaminophen (Tylenol) or ibuprofen (Advil, Motrin)) before and for up to 1 day after receiving the vaccine to lower the risk of fever and seizures from Pediarix.
If your child has a brain condition, talk to your child's provider before receiving Pediarix to make sure it's right for them. Your child's provider might hold off on giving your child the vaccine because there can be confusion between the side effects of Pediarix and the signs or symptoms of your child's brain condition.
Most people who receive Pediarix don't have any serious side effects. Side effects are generally mild and should go away on their own in a few days.
Make sure to keep a record of all your child's immunizations and show it to your child's provider or pharmacist before receiving any vaccine, including Pediarix, to make sure they're receiving all their vaccines on schedule.
Wait until your child is healthy to get Pediarix. This will help make sure their immune system protects them as best as it can. If your child has a mild sickness, such as a cold or low-grade fever, they can still get Pediarix. But if your child feels moderately to severely sick, wait until they recover. Ask your child's provider if you're not sure whether they can get this vaccine.
If your child experiences a severe reaction to Pediarix, you or your child's provider can report it to the vaccine adverse event reporting system (VAERS) website or by calling 1-800-822-7967.
Frequently asked questions about Pediarix
How to save using GoodRx
What are the risks and warnings for Pediarix?
Pediarix can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Severe allergic reactions
Risk factors: Latex allergy | Allergic reaction to other vaccines
As with any vaccine, there's a rare chance that your child might have a severe allergic reaction to Pediarix. The risk is higher if your child is allergic to latex since the tip caps of the prefilled syringes are made with natural rubber latex. Your provider might ask you and your child to stay at the pharmacy or clinic for a short period of time after you've received your vaccine to make sure your child can get proper care in case of a serious allergic reaction. Sometimes, these reactions can happen after you've already left the clinic. Get medical help right away if you notice symptoms of a severe allergic reaction, such as feeling faint, swelling of the face, closing of the throat, difficulty breathing, hives or rash, dizziness, nausea, or chest pain.
Higher risk of fever
Pediarix might raise your child's risk of developing a fever compared to receiving the vaccines separately. Monitor your child for fever after they get this vaccine, and ask your child's provider which medications you can give to them if needed.
Side effects from another whooping cough vaccine
Tell your child's provider or pharmacist if your child has ever had side effects within 2-3 days after receiving a pertussis vaccine, such as high fever (105 degrees F or higher), fainting, continuous crying lasting at least 3 hours, or seizures with or without a fever.
Lower response to Pediarix
Risk factors: Medical conditions or taking medications that weaken the immune system
Pediarix might not work as well in people with a weakened immune system. This can raise the risk of getting diphtheria, tetanus, and whooping cough, even after you've received the vaccine. If your child has any medical conditions (e.g., HIV (human immunodeficiency virus) or cancer) or takes medications that weaken the immune system (e.g., high-dose corticosteroids or transplant medications), talk to your child's provider before they receive Pediarix.
Fainting
Risk factors: Fainting after vaccines in the past
Fainting is associated with injectable vaccines, such as Pediarix. Signs of fainting include changes in vision, a tingling sensation, and stiffening or twitching of your arms and legs. Let your child's provider know if your child has fainted after vaccines in the past so they can be monitored.
Breathing issues (apnea) in premature babies
Risk factors: Premature birth
Vaccines that are injected into the muscle, like Pediarix, can raise the risk of apnea in babies who were born prematurely. This is a condition where babies have a temporary pause in their breathing, with or without a slowed heart rate or low oxygen level. If your baby was born prematurely, be sure to discuss the benefits and risks of receiving Pediarix with your child's provider.
Guillain-Barre syndrome (GBS)
Although very rare, some people have reported getting GBS after they've received vaccines containing tetanus toxoid-like Pediarix. GBS is a rare condition that causes muscle weakness and paralysis. Let your child's provider know right away if your child has experienced these symptoms, especially if it occurred within 6 weeks of receiving a tetanus toxoid-containing vaccine.
Pediarix dosage forms
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 0.5ml | 1 syringe | $87.00 | $87.00 |
Typical dosing for Pediarix
Pediarix is given as an injection into the thigh muscle (children younger than 1 year of age) or shoulder muscle (children 1 year and older) by a healthcare provider.
Primary series: This vaccine is typically a 3-dose series, given as 1 injection at age 2 months, 4 months, and 6 months. The first dose can be given as early as 6 weeks of age.
Note: Please see FAQs for more details about the use of Pediarix outside of the primary vaccine schedule.
How much does Pediarix cost?
Pediarix contraindications
Brain problem: Having seizures for a long time, not able to respond normally, or having a coma within 7 days of a previous dose of a pertussis-containing vaccine
Progressive seizure disorders: Having seizures for a long time after receiving a previous dose of a pertussis-containing vaccine
Pediarix images
Get savings updates for Pediarix
Receive price alerts, news, and other messages from GoodRx about Pediarix and other healthcare topics and relevant savings offers.By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.
Browse medications
View AllResearch prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.