Nystatin/triamcinolone is a combination topical medication used to treat certain fungal skin infections caused by yeast. Nystatin is an antifungal that kills the yeast and triamcinolone is a corticosteroid that eases skin itching and redness from the infection. Nystatin/triamcinolone is available as a cream and an ointment, and can be used by adults and children ages 2 years and older. This medication is applied to the skin, typically twice a day. Most people experience few to no side effects while using nystatin/triamcinolone as directed. But there have been rare reports of itching and burning at the application site.
Nystatin/triamcinolone is a combination of two medications:
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Blistering, burning, dryness, itching, peeling, or other sign of irritation not present before use of this medicine
Check with your doctor as soon as possible if any of the following side effects occur:
Acne or oily skin
increased hair growth, especially on the face
increased loss of hair, especially on the scalp
reddish purple lines on arms, face, legs, trunk, or groin
thinning of skin with easy bruising
Many of the above side effects are more likely to occur in children, who may absorb greater amounts of this medicine.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Don't apply nystatin/triamcinolone over your face unless a healthcare professional instructed you to do so. This is because nystatin/triamcinolone contains triamcinolone, which is a medium strength topical steroid. Using it on your face can cause you to absorb too much triamcinolone, which can put you at higher risk for side effects, such as skin thinning, stretch marks, spider veins, burning, itching, or rash. If too much triamcinolone builds up in your body, you might experience more serious side effects, such as joint pain, blood sugar changes, or fainting.
Nystatin/triamcinolone is only FDA-approved to treat certain fungal infections, not acne. In general, triamcinolone and other topical steroids can cause or worsen acne as a side effect. If you have acne problems, talk to your dermatologist before starting this medication. To minimize acne side effects, it's best to use the smallest amount of nystatin/triamcinolone for the shortest amount of time possible.
Nystatin/triamcinolone is only FDA-approved to treat certain fungal skin infections, not eczema. If you have eczema, talk to your dermatologist about possible treatment options for you. Sometimes, topical triamcinolone might be recommended to help ease redness and itching during an eczema flare. If so, your dermatologist will only prescribe triamcinolone as a single medication, not in combination with nystatin.
Nystatin/triamcinolone can typically start to relieve symptoms in the first few days of treatment. Your dermatologist will let you know how long to use nystatin/triamcinolone for depending on how serious your infection is. Typically, the maximum length of treatment is 25 days.
For nystatin/triamcinolone topical ointment, you can place a thin layer of the ointment to the affected area(s) of your skin infection until it heals. For nystatin/triamcinolone topical cream, you can gently massage the medication into the skin until it disappears. Talk to your prescriber if you have questions about how to apply this medication.
Nystatin/triamcinolone shouldn't be used to treat ringworm since this medication doesn't work on the fungi that cause the infection. If you aren't sure what type of fungal skin infection you have, talk to your dermatologist.
Yes, nystatin/triamcinolone can expire. Don't use this topical medication if it's expired. Always check the expiration date of your medication before using it. Expired nystatin/triamcinolone might not work well and can raise your risk of an infection. If your medication has expired, you can get a refill at the pharmacy if there are refills left on the original prescription. You might need to make an appointment with a healthcare professional so they can examine your skin and write a new prescription, if appropriate.
Nystatin/triamcinolone shouldn't be used long-term. Before starting this medication, ask your dermatologist how long your treatment should last. If your symptoms of skin infection aren't better or have gotten worse after 25 days, stop this medication and talk with your dermatologist right away.
Nystatin/triamcinolone can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Tell your dermatologist before using nystatin/triamcinolone if you've ever had an allergic reaction to nystatin or triamcinolone before. Watch out for signs and symptoms of allergic reactions, such as swollen skin, rash, itchy skin, or other skin irritation. Please stop using nystatin/triamcinolone and tell your dermatologist if you have these signs and symptoms. Get medical help right away if the swelling is severe or if you're having trouble breathing.
Nystatin/triamcinolone contains triamcinolone, which is a topical steroid. In some rare cases, using a topical steroid for a long time and over a large skin area can cause a medical condition called adrenal suppression. This is when your adrenal gland starts to make less steroid hormones because the body is depending on the medication instead. And if you suddenly stop using triamcinolone, you can experience serious side effects.
In adults, symptoms of withdrawal include fever, joint or muscle pain, and low energy. In children, symptoms often include stunted growth, weight gain, and headaches. To prevent adrenal suppression from happening, your dermatologist will prescribe the lowest possible dose of nystatin/triamcinolone that works well for you for the shortest amount of time. If you need to use nystatin/triamcinolone for a long period of time or for a large area, your dermatologist might ask you to do some lab work to test how well your adrenal gland works. Let your dermatologist know if you have symptoms of withdrawal. Don't suddenly stop using nystatin/triamcinolone without talking to your care team first.
Nystatin/triamcinolone is available as a cream and an ointment
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Treatment and symptom relief (e.g., itching, irritation, redness) of the following fungal skin infections: