Lofexidine is part of the Alpha-2 Agonists class and treats Opioid Dependence. Alpha-2 agonists are used to treat hypertension, opioid dependence, ADHD, and spasticity. They work by lowering blood pressure, reducing hot flashes, and relieving withdrawal symptoms, and controlling impulsive behavior. Lofexidine is only available as a generic drug.

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