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Lidocaine / Hydrocortisone Coupon - Lidocaine / Hydrocortisone 28.35g of 3%/0.5% tube of cream

lidocaine / hydrocortisone

Generic Ana-Lex
Used for Hemorrhoids
Used for Hemorrhoids

Lidocaine / hydrocortisone is a prescription pain relief cream used to treat adults with hemorrhoids, anal fissure, and other inflammatory skin conditions. The anal cream is a combination of two medications, lidocaine (local anesthetic) and hydrocortisone (corticosteroid). These two medications work together to numb pain and relieve itching and inflammation. Lidocaine / hydrocortisone comes as a cream that you apply 2 times a day. Common side effects include temporary burning and itching at the application site.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on October 13, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Lidocaine / hydrocortisone?

What is Lidocaine / hydrocortisone used for?

Relieving itching, pain, soreness, and swelling due to:

How Lidocaine / hydrocortisone works

Lidocaine / hydrocortisone is a combination of two different topical medications.

  • Lidocaine is a local anesthetic. It eases pain and skin irritation by numbing the nerves and making them less sensitive to pain or irritation.

  • Hydrocortisone is a topical corticosteroid. When it’s used on the skin, it lowers the amount of inflammatory chemicals that cause redness, itching, and swelling. This helps to reduce skin inflammation.

Are you looking for information on lidocaine alone or hydrocortisone alone instead?

Drug Facts

Common BrandsAna-Lex (brand name no longer available)
Drug ClassLocal anesthetic / Corticosteroid
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$67.31(save 77.68%)
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$15.02
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What are the side effects of Lidocaine / hydrocortisone?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Temporary stinging or burning
  • Temporary pale skin
  • Skin redness

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Burning or stinging sensation of the skin

paleness or redness of the skin

swelling of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Lidocaine / hydrocortisone

thumbs-up

Pros

Works directly in the area to relieve anal symptoms

Combines two different topical medications

thumbs-down

Cons

Need to use twice a day

Can be uncomfortable and messy to apply

pharmacist-tips

Pharmacist tips for Lidocaine / hydrocortisone

pharmacist

  • Wash your hands before and after using lidocaine / hydrocortisone to prevent getting the medication in your eyes. If it does get into your eyes, wash your eyes with water or saline and contact your healthcare team if irritation doesn't go away.

    • Don’t put lidocaine / hydrocortisone in your eyes, nose, mouth, or ears. Get medical attention right away if you think that your child might’ve accidentally swallowed this medication.

      • It's best to use the bathroom before applying lidocaine / hydrocortisone rectally. Going to the bathroom after using the medication might cause you to wash or wipe off the medication before it starts to work.

        • Before applying lidocaine / hydrocortisone, clean the area with water and let it dry. Some products include a cleansing wipe that you can use.

          • Lidocaine / hydrocortisone can cause temporary stinging or burning on open areas of the skin where the cream was applied. This should go away on its own, but if it doesn’t, let your prescriber know.

            • If your symptoms don’t improve or get worse while using lidocaine / hydrocortisone, talk to your prescriber. You might need a different treatment.

              • Store lidocaine / hydrocortisone up and away and out of children's reach and sight. This prevents them from accidentally swallowing medication that was left out. Always put it away every time you use it.

                faqs

                Frequently asked questions about Lidocaine / hydrocortisone

                Is lidocaine / hydrocortisone a steroid?
                Lidocaine / hydrocortisone contains topical hydrocortisone, a steroid that helps reduce skin inflammation. Since it's applied to the skin, only small amounts of the medication are absorbed into the bloodstream. This makes it less likely to cause certain serious side effects linked to steroids that you take by mouth. Make sure to use lidocaine / hydrocortisone as directed by your healthcare team to lower the risk of side effects.
                How to apply lidocaine / hydrocortisone cream?
                Lidocaine / hydrocortisone comes in different forms, some with an applicator and some without. Be sure to follow the instructions for your specific product. Before applying, clean the affected area with water or a moist wipe and pat dry with toilet paper. If you're not using an applicator, apply a thin layer of cream around the anal area using your finger. If your product comes with an applicator, attach it to the tube, insert the applicator into the rectum and squeeze the cream for a few seconds. Wash your hands immediately before and after application.
                Does lidocaine / hydrocortisone help with itching?
                Yes. Lidocaine / hydrocortisone is a combination of two topical medications, lidocaine and hydrocortisone. Lidocaine is a local pain anesthetic, which means it numbs pain and reduces skin irritations in the application area. Hydrocortisone is a topical steroid. It can reduce inflammation in the application area, which helps with swelling and itching.
                Does lidocaine / hydrocortisone reduce swelling?
                Yes. Lidocaine / hydrocortisone contains hydrocortisone which can help reduce swelling where it's applied.
                Can you mix lidocaine and hydrocortisone if you don't have lidocaine / hydrocortisone?
                It's not recommended to mix topical lidocaine and hydrocortisone for hemorrhoid symptoms, even if you have them at home.Lidocaine / hydrocortisone is made to give the right amount of medication with each use, but mixing products on your could lead to the wrong dose. It's important to follow up with your healthcare team if you have rectal itching, pain, or soreness. Using over-the-counter pain relief on your own could delay proper treatment and potentially worsen your symptoms.
                Can lidocaine / hydrocortisone cause constipation?
                While constipation isn't a common side effect of lidocaine / hydrocortisone, it's a common cause of hemorrhoids. If you experience constipation while using this cream, consider adding more fiber to your diet and drinking more water. This would help to reduce straining during bowel movements, which can help lessen how often you get hemorrhoids.
                Can lidocaine / hydrocortisone cause diarrhea?
                Diarrhea isn't a common side effect of lidocaine / hydrocortisone, but it's been linked to hemorrhoids. If you have diarrhea for longer than 2 days, let your healthcare team know right away. Prolonged or serious diarrhea can be a warning sign for more serious medical conditions.
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                What are the risks and warnings for Lidocaine / hydrocortisone?

                Lidocaine / hydrocortisone can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Change in stress hormones levels

                • Risk factors: Using lidocaine / hydrocortisone for a long period of time | Using more lidocaine / hydrocortisone than recommended | Covering applied areas with a bandage | Young children

                  If too much topical steroid is absorbed through the skin, it can interrupt your body's ability to make stress hormones and affect many bodily functions. Although lidocaine / hydrocortisone contains a topical steroid, a topical steroid, this is rare. But your risk is higher if you apply lidocaine / hydrocortisone for a long time or apply it over larger areas of skin. To prevent changes in hormone levels, your healthcare team will prescribe the lowest possible dose of lidocaine / hydrocortisone for the shortest amount of time.

                  In addition, if you suddenly stop using lidocaine / hydrocortisone after having done so for a long time and over a large skin area, you might experience topical steroid withdrawal (TSW). Some symptoms include itchy, burning, or flaky skin. Don't suddenly stop using this medication without talking to them first.

                  risk-warning

                  Skin infection

                  Lidocaine / hydrocortisone can lower your body's ability to fight infections, including infections on your skin. It's especially important to treat skin infections with an appropriate antifungal or antibacterial if you're using lidocaine / hydrocortisone. If you notice redness, pain, swelling, or pus where you are applying this medication, stop using it and talk to your prescriber right away.

                  dosage

                  Lidocaine / hydrocortisone dosage forms

                  The average cost for 1 tube of 28.35g of 3%/0.5% of Lidocaine / hydrocortisone is $15.02 with a free GoodRx coupon. This is 77.68% off the average retail price of $67.31.
                  kit
                  Kit
                  DosageQuantityPrice as low asPrice per unit
                  14 tubes of 3%/0.5% cream1 kit$29.82$29.82
                  20 tubes of 3%/0.5% cream1 kit$40.73$40.73
                  20 tubes of 3%/1% cream1 kit$51.65$51.65
                  24 tubes of 2%/2% cream1 kit$40.85$40.85
                  20 tubes of 3%/2.5% gel1 kit$50.54$50.54
                  tube of cream
                  Tube of cream
                  DosageQuantityPrice as low asPrice per unit
                  28.35g of 3%/0.5%1 tube$15.02$15.02
                  85g of 3%/0.5%1 tube$27.06$27.06
                  tube of gel
                  Tube of gel
                  DosageQuantityPrice as low asPrice per unit
                  100g of 2.8%/0.55%1 tube$74.20$74.20

                  Typical dosing for Lidocaine / hydrocortisone

                  Apply a thin layer to the affected area(s) 2 times daily.

                  interactions

                  Interactions between Lidocaine / hydrocortisone and other drugs

                  Lidocaine / hydrocortisone may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Lidocaine / hydrocortisone. Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  • Dihydroergotamine
                  • Dronedarone
                  • Saquinavir
                  • Vernakalant

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  drug-cost

                  How much does Lidocaine / hydrocortisone cost?

                  To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                  Lidocaine / hydrocortisone (generic)
                  GoodRx lowest price

                  $15.02

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                  contraindications-icon

                  Lidocaine / hydrocortisone contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Lidocaine / hydrocortisone will not be safe for you to take.
                  alternatives

                  What are alternatives to Lidocaine / hydrocortisone?

                  There are a number of medications that your doctor can prescribe in place of Lidocaine / hydrocortisone. Compare a few possible alternatives below.
                  Lidocaine / hydrocortisone
                  Used for:

                  Relieving itching, pain, soreness, and swelling due to:

                  $15.02 Lowest GoodRx priceView Prices
                  Hydrocortisone (Anusol-HC)
                  Used for:
                  $16.79 Lowest GoodRx priceView Prices
                  Analpram HC (hydrocortisone / pramoxine)
                  Used for:

                  • Itching and inflammation from certain skin conditions, like psoriasis

                  $40.47 Lowest GoodRx priceView Prices
                  images

                  Lidocaine / hydrocortisone images

                  This medicine is Colorless Tube Of Cream.
                  white - Lidocaine Hydrochloride / Hydrocortisone Acetate 3%-0.5% Topical Cream
                  This medicine is White Tube Of Cream.white - Lidocaine Hydrochloride / Hydrocortisone Acetate 3%-0.5% Topical Cream

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                  References

                  Best studies we found

                  Centers for Disease Control and Prevention. (2024). About the PROTECT initiative.

                  PureTek Corporation. (2023). Lidocaine HCl- Hydrocortisone acetate- lidocaine hcl and hydrocortisone acetate cream [package insert]. DailyMed.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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