Anal fissures are small tears in the lining of the anus. Superficial tears will heal themselves, but decreased blood flow due to muscle spasm or constipation can cause a chronic issue. Fissures can bleed, cause pain during a bowel movements, and itch.
Common drug classes used to treat anal fissures are nitrates (Rectiv) for pain and acetylcholine release inhibitors (Botox) to relieve spasm. Using stool softeners or laxatives can help prevent pain during bowel movements. Surgery is also an option for chronic anal fissures.