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Jynneos is a brand-name medicationLearn how to save on brand-name medications

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About Jynneos

SMALLPOX and MONKEYPOX VACCINE reduces the risk of smallpox and monkeypox (mpox). It works by helping your immune system learn how to fight off a future infection. It is still possible to get smallpox or monkeypox (mpox) after receiving this vaccine, but the symptoms may be less severe or not last as long. It does not treat smallpox or monkeypox (mpox).

Get Jynneos for as low as $308.99, which is 16% off the average retail price of $367.34 for the most common version, by using a GoodRx coupon. Learn about saving on prescription medications with GoodRx Companion.

Jynneos

Jynneos

Drug Info Brand-name medications Side Effects Dosage Medicare

Jynneos

This vaccine is free with most private insurance, Medicare Part D, and Medicaid plans. Without coverage, save with a GoodRx coupon.

Learn more about vaccine coverage

Popular offers

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Check your prescription

Pricing is calculated based on your prescription details.

Standard GoodRx price

*Prices subject to change without notice. Sales tax may apply and is not included.

$

309.05

Retail: $365.99

GoodRx coupon prices last updated on 09/10/26.

Prescription not at CVS Pharmacy?

Start a transfer to use this coupon.

Ways to save on Jynneos

These programs and tips can help make your prescription more affordable

Gold coin

Other Vaccinations

Fluzone High-Dose

Related conditions

Jynneos prices by dosage

Jynneos vial prices

Dosage	Quantity	Retail price	GoodRx price

0.5ml

1 vial

$365.99