The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Cough, runny or stuffy nose, and other symptoms of an upper respiratory tract infection 6%)
- Diarrhea (6%)
Less Common Side Effects
- Nausea and vomiting
- Passing gas
- Weakness
- Stomach discomfort
- Headache
Jentadueto serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Buildup of lactic acid: confusion, feeling weak, fast or slow heartbeat, rapid breathing, no appetite, nausea, vomiting
- Inflamed pancreas: upper stomach pain, fever, nausea, vomiting
- Severe skin or allergic reactions: rash, blisters, sores, trouble breathing, swelling
Source: DailyMed
The following Jentadueto side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
- High lactic acid level—muscle pain or cramps, stomach pain, trouble breathing, general discomfort and fatigue
- Low vitamin B12 level—pain, tingling, or numbness in the hands or feet, muscle weakness, dizziness, confusion, trouble concentrating
- Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Severe joint pain
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Cough
- Diarrhea
- Runny or stuffy nose
- Sore throat



