Typical dosage for Hydroxyprogesterone
- Lack of or irregular menstrual periods:
- Single dose treatment or cyclic therapy (taking estrogen therapy): Your provider will inject 375 mg into your buttock muscle one time.
- Cyclic therapy (not taking estrogen therapy): Your provider will inject 250 mg into your buttock muscle on day 15 of the 28-day cycle planned by you and your provider. As part of treatment, provider will also give you estradiol valerate (Delestrogen) on different days of the cycle.
- Advanced uterine cancer: Your provider will inject 1,000 mg into your buttock muscle one or more times a week. Use no more 7,000 mg per week.
- Testing for estrogen production: Your provider will inject 250 mg into your buttock muscle one time. If your body produces estrogen, you can expect a menstrual period 7 to 14 days after the injection. Your provider can order another injection 28 days later if needed.
