Typical dosage for Herceptin
Herceptin is given by a healthcare provider as an injection into a vein (IV) or as an injection under the skin (subcutaneous, SQ).
When given IV, the dose depends on your body weight. Your healthcare provider will determine the appropriate dose for you each time you receive the medication.
HER2-positive, breast cancers
- IV injection: The typical dose is 4 mg/kg of bodyweight IV for the first injection, and then 2 mg/kg given once a week. It can also be given as 8 mg/kg for the first injection, and then 6 mg/kg every 3 weeks thereafter.
- SQ injection (Herceptin Hylecta brand only): Herceptin Hylecta for injection under the skin contains trastuzumab and hyaluronidase. The typical dose is 600 mg/10,000 units (trastuzumab/hyaluronidase) given under the skin every 3 weeks. The SQ injection is a flat dose and isn’t dependent on weight.
HER2-positive, metastatic stomach cancer: The typical dose is 8 mg/kg IV for the first injection, and then 6 mg/kg every 3 weeks thereafter.
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