Key takeaways:
The recovery from traumatic brain injury (TBI) varies from person to person. The type of recovery you need depends on your level of injury.
After TBI, there are both physical and behavioral changes you’ll need to recover from. Preventing further damage is important in every recovery.
Medications, rehabilitation, and other therapies are helpful in recovery from TBI. Supportive programs can provide additional aid.
Traumatic brain injury (TBI) is damage to the brain after trauma to the head. Recovery from TBI is a process that takes time. That process will vary from person to person depending on how severe the injury is. But there are things you can do to reduce complications and improve your chances of recovery.
People with mild TBI usually recover over time, but they must be very careful to avoid repeat injuries. If someone has another serious head injury before they recover, it can worsen quickly and cause severe brain swelling.
This is “second impact syndrome,” and it can be so serious it leads to death. Athletes who return too soon after a concussion are at high risk for second impact syndrome.
Mild TBI that keeps happening over time can give rise to more serious issues. This is chronic traumatic encephalopathy (CTE). CTE is more common in people who have repetitive injuries. People at high risk include those who play football, ice hockey, soccer, and rugby. Boxers and those in active duty also have a high risk.
Ongoing symptoms of CTE can include:
Memory problems
Speech problems
Decreased coordination
Attention deficits
Suicidal behaviors
After TBI there can be changes in how you think, understand, and behave. These complications may include:
Agitation
Disorientation
Mood changes
Aggressiveness
Impulsivity and irritability
Poor judgment
Trouble communicating
Slow thinking
Difficulty concentrating
Amnesia (memory problems)
If you have amnesia after a TBI, you may not recall events before or after the injury. That’s because the memory connections in the brain get altered as a result of TBI. You may forget events that happened right before the injury (retrograde amnesia). Or you may have trouble forming new memories of facts or events after the injury (anterograde amnesia).
In addition to behavior changes, TBI can have medical consequences. This is more likely to occur with moderate or severe TBI.
Medical complications in early stages after moderate or severe TBI may include:
Infections
Increased blood pressure, heart rate, and body temperature
Hydrocephalus (abnormal buildup of brain fluid)
Deep vein thrombosis (DVT)
Wounds (skin breakdown and ulcers)
Pituitary gland disorders (like diabetes insipidus)
Long-term medical complications after TBI include:
Headaches (may continue up to 1 year after injury)
Heterotopic ossification (abnormal bone formation usually in the hip or knee in TBI)
Spasticity (abnormal increase in muscle tone)
Over half of people with severe TBI develop post-traumatic epilepsy (PTE). Changes in the brain may include:
Hemorrhage
Scarring
Lack of oxygen
Swelling
Inflammation
These changes lead to events that may continue to deteriorate the brain for months to years. In PTE, the brain circuits reorganize, causing a change in its electrical impulses. This can lead to seizures.
Some people may have the first seizure many years after injury. If you have a family member with epilepsy, this increases your odds of PTE after TBI.
Treatments to help recovery from TBI can vary. Some people with mild TBI may only need rest and pain medication, whereas people with severe TBI may need intensive care treatment.
For a serious TBI, treatment in the short term may include:
Medical stabilization: The medical team will make sure there is proper blood flow, pressure, and oxygenation to the brain. Your provider may recommend inducing a coma. This will let the brain rest while it heals.
Surgery: People with moderate or severe injuries may need surgery. Sometimes a surgeon will remove a bone flap from the skull to drain blood and release pressure in the brain. Or they may drill holes in the skull bones and place a catheter.
Some medications may help treat symptoms and complications after TBI. In long-term recovery, you may need treatment for:
Headaches: Treatment may consist of physical therapy, nerve blocks, or injections. Some medications — such as divalproex, gabapentin, and amitriptyline — might also help.
Seizures: Antiepileptic medications in the first week after injury may help prevent early seizures after TBI. But many develop PTE later on. Medications may include levetiracetam, phenytoin, and lamotrigine, among others. But they don’t always work.
Depression: Medications like Celexa (citalopram) and Zoloft (sertraline) may help for depression. Positive environments may also improve emotional well-being.
Behavior changes: You may need treatment for mood and behavior changes. For example, buspirone for stabilizing mood, modafinil for focus, and propranolol for aggression.
For mild TBI, recovery can happen in a matter of weeks. Sometimes recovery can occur months or even years after the injury. It will depend on the level of impairment from your injury.
Recovery in severe TBI may begin with opening the eyes and regaining some movements and purposeful behaviors. Then, you may go through periods of confusion, agitation, and poor awareness. Improved memory and mobility along with a return to proper behavior means there is significant improvement.
Ongoing recovery can last for months to years. TBI survivors will likely need support as they seek to recover. This can include support from rehabilitation and social services after returning home.
People with TBI may need rehabilitation at a hospital or clinic. The type of therapy will depend on:
Severity of symptoms
Degree of mobility
Ability to take part in therapies
Medical stability
Rehabilitation includes physical and occupational therapy for mobility and activities of daily life. Speech and language therapists can help with any swallowing and speech problems.
Treatment for difficulty swallowing includes:
Changes in posture and position during swallowing
Strengthening exercises
Special swallowing techniques
Electrical stimulation
Changes in food consistencies (more liquid, blended, mashed, or ground foods)
Once you return to the home environment after TBI, you may need some help going back to life roles. After the initial recovery, you may have an ongoing need for:
Disability exams
Vocational rehabilitation
Driving tests
Counseling
TBI survivors may also need to use mobility aids or other assistive devices. This can be an ongoing expense, but there are programs and financial assistance to help.
Family and caregivers should learn to cope with impairments and provide support when possible. It’s also important to be realistic on what to expect.
People with mild TBI tend to recover well. But some may continue to have memory problems. They’re also at risk of substance misuse and psychiatric disease.
Most people with moderate TBI recover fairly well, but about 25% will show some disability. In contrast, only about 25% of those with severe TBI recover well. And most will have a higher level of disability.
Experts consider TBI a chronic, lifelong health condition. People who have had moderate to severe TBI seem to have a shorter life span.
TBI may have many neurological consequences. And, over the years, there can be further deterioration. Those who had a TBI may have higher chances of:
ALS (amyotrophic lateral sclerosis)
Recovering from traumatic brain injury (TBI) takes time. And there may be long-lasting disabilities to deal with. But there are programs and supportive therapies that can assist your recovery. If you or a loved one had a TBI, learn as much as you can about the condition. Patience, flexibility, and community resources will help you get through the recovery process.
American Association of Neurological Surgeons. (2020). Traumatic brain injury.
Cantu, R. C. (2001). Posttraumatic retrograde and anterograde amnesia: Pathophysiology and implications in grading and safe return to play. Journal of Athletic Training.
Centers for Disease Control and Prevention. (n.d.). Moderate to severe traumatic brain injury is a lifelong condition.
May, T., et al. (2022). Second impact syndrome. StatPearls.
National Institute of Diabetes and Digestive and Kidney Diseases. (2021). Diabetes insipidus.
National Institute of Neurological Disorders and Stroke. (2022). Hydrocephalus fact sheet.
National Institute of Neurological Disorders and Stroke. (2022). Spasticity.
Sharma, S., et al. (2021). Neuropathophysiological mechanisms and treatment strategies for post-traumatic epilepsy. Frontiers in Molecular Neuroscience.
Sun, E., et al. (2022). Heterotopic ossification. StatPearls.