Fluoroplex
Fluoroplex (fluorouracil) 1% cream is used to treat actinic keratosis (scaly pre-cancerous spot or growth on the skin) in adults. It belongs to the antimetabolite drug class, which works by stopping skin cells from dividing and growing. It's applied to the affected skin area(s) twice per day, usually for 2 to 6 weeks. Side effects of this medication include skin burning, crusting, and itching.
Note: Fluoroplex (fluorouracil) 1% cream has been discontinued. Talk to your dermatologist about other topical fluorouracil products for actinic keratosis.
What is Fluoroplex (fluorouracil) 1% cream?
What is Fluoroplex (fluorouracil) 1% cream used for?
- Actinic (or solar) keratosis (scaly pre-cancerous spot or growth on the skin)
How Fluoroplex (fluorouracil) 1% cream works
Fluoroplex (fluorouracil) 1% cream is an antimetabolite. It works by getting in the way of cells making copies of their genetic material. When applied on pre-cancerous or cancerous skin cells, Fluoroplex (fluorouracil) 1% cream prevents them from being able to grow.
Drug facts
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Common questions about Fluoroplex (fluorouracil) 1% cream
No, Fluoroplex (fluorouracil) 1% cream has been discontinued and is no longer available in the United States. Talk to your dermatologist about other available topical fluorouracil products that can treat actinic keratosis.
Typically, you need to apply Fluoroplex (fluorouracil) 1% cream for 2 to 6 weeks. But if you're not able to tolerate some of the side effects, such as burning or redness, let your dermatologist know. They might suggest that you stop this medication earlier and talk with you about other options.
How long it takes for Fluoroplex (fluorouracil) 1% cream to work can differ from person to person, depending on how severe your condition is. Your skin should begin to improve within 2 to 6 weeks of starting the medication. Talk to your dermatologist if you're concerned with how well Fluoroplex (fluorouracil) 1% cream is working to treat your skin condition.
Similar to other topical fluorouracil medications, the common side effects of Fluoroplex (fluorouracil) 1% cream are skin reactions at the application site. These reactions incude pain, itching, burning, irritation, redness, and swelling. More rare side effects include changes in skin color and scarring.
The side effects of Fluoroplex (fluorouracil) 1% cream are generally related to skin irritation, such as pain, itching, burning, and redness. These reactions can look serious, but should improve over time. But Fluoroplex (fluorouracil) 1% cream can cause severe problems to unborn babies if used during pregnancy. For this reason, all topical fluorouracil products should be avoided during pregnancy.
No, don't apply fluorouracil cream to broken or damaged skin. Doing so will cause severe pain and also can cause some of the medication to get absorbed into your blood, which can cause side effects to the other parts of your body. If the area of skin where you're applying Fluoroplex (fluorouracil) 1% cream is damaged, stop using Fluoroplex (fluorouracil) 1% cream and contact your dermatologist for further instruction.
Yes, Fluoroplex (fluorouracil) 1% cream can affect healthy skin. You can apply Fluoroplex (fluorouracil) 1% cream on the affected area(s) using your fingertips or an applicator. Try as much as possible to not touch the surrounding healthy skin. It's also important to wash your hands right away very well with soap and water after applying the cream, especially if you're applying the medication with your fingertips.
Since Fluoroplex (fluorouracil) 1% cream makes your skin more sensitive to light, it's a good idea to use sunscreen and wearing protective clothing (e.g., hats, long-sleeved shirts) when going outside. But the manufacturer doesn't say how soon you can put on sunscreen after applying Fluoroplex (fluorouracil) 1% cream. The recommendation for Carac, another brand of fluorouracil cream, is to wait at least 2 hours before putting sunscreen on the affected area(s). It's best to ask your dermatologist how soon you can put sunscreen over the affected area(s) treated with Fluoroplex (fluorouracil) 1% cream.
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Fluoroplex (fluorouracil) 1% cream dosage
Tube of cream| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 30g of 1% | 1 tube | $897.08 | $897.08 |
Typical dosage for Fluoroplex (fluorouracil) 1% cream
Interactions between Fluoroplex (fluorouracil) 1% cream and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Brivudine
- Measles Virus Vaccine, Live
- Mumps Virus Vaccine, Live
- Rotavirus Vaccine, Live
- Rubella Virus Vaccine, Live
- Tegafur
- Varicella Virus Vaccine, Live
- Zoster Vaccine, Live
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acenocoumarol
- Adenovirus Vaccine
- Allopurinol
- Azanidazole
- Bacillus of Calmette and Guerin Vaccine, Live
- Benznidazole
- Cholera Vaccine, Live
- Cimetidine
- Dengue Tetravalent Vaccine, Live
- Influenza Virus Vaccine, Live
- Isoconazole
- Levoleucovorin
- Methotrexate
- Metronidazole
- Nimorazole
- Ornidazole
- Oxypurinol
- Phenprocoumon
- Poliovirus Vaccine, Live
- Secnidazole
- Smallpox Vaccine
- Tamoxifen
- Tinidazole
- Typhoid Vaccine, Live
- Warfarin
- Yellow Fever Vaccine
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Fosphenytoin
- Leucovorin
- Levamisole
- Phenytoin
- Thiamine
How much does Fluoroplex (fluorouracil) 1% cream cost?
$897.08
