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Estrogel (estradiol) is used for symptoms of menopause like hot flashes, night sweats, and mood changes. It is slightly more popular than comparable drugs. There are currently no generic alternatives to Estrogel.
GoodRx has partnered with InsideRx and Ascend Therapeutics to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Estrogel is covered by most Medicare and insurance plans.
With the Patient Assistance Program from PAN Foundation, contact the program to see how they can financially help you out.

| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 50g of 0.06% | 3 pumps | $991.91 | $638.81 |
GoodRx coupon prices last updated on 05/01/26.