Dexbrompheniramine/Pseudoephedrine is part of the Antihistamine / Alpha-1 Agonist Combinations class and treats Nasal Congestion, Allergic Rhinitis and Cold Symptoms. Antihistamine / alpha-1 agonist combinations are used to treat allergic rhinitis, nasal congestion, and cold symptoms. They work by shrinking blood vessels in the nose for congestion and by blocking histamine which causes the symptoms of stuffy nose, runny nose, itchy throat, and sneezing. Dexbrompheniramine/Pseudoephedrine is only available as a generic drug.