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Desloratadine

Desloratadine Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on May 3, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Sore throat (4%)
  • Dry mouth (3%)
  • Sleepiness (2%)
  • Muscle pain (2%)
  • Fatigue (2%)

Desloratadine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction: itchy, red rash (hives); shortness of breath; chest tightness; swelling of lips, tongue, throat, face, or eyes
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Source: DailyMed

The following Desloratadine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Anaphylaxis, such as, cough, difficulty swallowing, dizziness, fast heartbeat, hives, itching, puffiness or swelling of eyelids or around the eyes or face or lips or tongue, shortness of breath, skin rash, tightness in chest, unusual tiredness or weakness, wheezing

dyspnea, such as, shortness of breath, difficult or labored breathing, tightness in chest, wheezing

edema, such as, swelling

pruritus, such as, itching skin

rash

tachycardia, such as, fast, pounding, or irregular heartbeat or pulse

urticaria, such as, hives or welts, itching, redness of skin, skin rash.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Less common

Dizziness

dry mouth

dysmenorrhea, such as, difficult or painful menstruation

dyspepsia, such as, acid or sour stomach, belching, heartburn, indigestion, stomach discomfort , upset or pain,

fatigue, such as, unusual tiredness or weakness

myalgia, such as, joint pain, swollen joints, muscle aching or cramping, muscle pains or stiffness, difficulty in moving

pharyngitis, such as, body aches or pain, congestion, cough, dryness or soreness of throat, fever, hoarseness, runny nose, tender swollen glands in neck, trouble in swallowing, voice changes.

somnolence, such as, sleepiness or unusual drowsiness

nausea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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