The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Dry mouth
- Blurry vision
- Nausea
- Vomiting
- Constipation
- Sleepiness
- Dizziness
- Confusion
- Anxiety
- Restlessness
Less Common Side Effects
- Tremors
- Trouble sleeping (insomnia)
- Bladder problems
- Sun sensitivity
- Weight gain or weight loss
Desipramine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or behaviors
- Serotonin syndrome: fast heartbeat, sweating, muscle stiffness or spasms, fever, and confusion
- Heart attack: chest pain, cold sweats, left arm pain, difficulty breathing
- Stroke: sudden numbness, weakness, confusion, or difficulty talking
- Serious allergic reaction: difficulty breathing, hives, itching, fast heartbeat, tightness in the throat, dizziness, swelling in the face or tongue
Source: DailyMed
The following Desipramine side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Abdominal or stomach pain
black, tarry stools
blurred or double vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or discomfort
confusion about identity, place, and time
convulsions
cough or hoarseness
dark urine
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fainting
fast, irregular, pounding, or racing heartbeat or pulse
inability to move the arms, legs, or facial muscles
inability to speak
irritability
light-colored stools
lightheadedness
loss of appetite
loss of bladder control
muscle spasms or jerking of all extremities
nightmares
pain or discomfort in the arms, jaw, back, or neck
painful or difficult urination
pinpoint red or purple spots on the skin
pounding in the ears
rash
restlessness
seeing, hearing, or feeling things that are not there
shakiness and unsteady walk
slow speech
sore throat and fever
sores, ulcers, or white spots on the lips or in the mouth
stiffness of the limbs
sudden loss of consciousness
sweating
swelling
swollen glands
talking, feeling, and acting with excitement
trouble sleeping
twisting body movements
unsteadiness, trembling, or problems with muscle control or coordination
unusual bleeding or bruising
unusual tiredness or weakness
vomiting
yellow eyes and skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Abdominal or stomach cramps
bigger, dilated, or enlarged pupils (black part of the eye)
decrease in the frequency of urination
decrease in urine volume
decreased interest in sexual intercourse
difficulty in passing urine (dribbling)
hair loss or thinning of the hair
inability to have or keep an erection
increased in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
increased sensitivity of the eyes to light
loss in sexual ability, desire, drive, or performance
swelling of the breasts or breast soreness in both females and males
swelling or inflammation of the mouth
unexpected or excess milk flow from breasts in females
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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